A Close Look at the Clinical Efficacy of Rho-Associated Protein Kinase Inhibitor Eye Drops for Fuchs Endothelial Corneal Dystrophy

The current understanding on the clinical efficacy of Rho-associated protein kinase (ROCK) inhibitor for treating Fuchs endothelial corneal dystrophy is summarized to clarify whether the “off-label” ROCK-inhibitor eye-drop application are appropriate. ROCK-inhibitor eye drops may eventually be deeme...

Descripción completa

Detalles Bibliográficos
Autores principales: Kinoshita, Shigeru, Colby, Kathryn A., Kruse, Friedrich E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cornea 2021
Materias:
Invited Submission
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423139/
https://www.ncbi.nlm.nih.gov/pubmed/34481406
http://dx.doi.org/10.1097/ICO.0000000000002642
_version_ 1783749403752792064
author Kinoshita, Shigeru
Colby, Kathryn A.
Kruse, Friedrich E.
author_facet Kinoshita, Shigeru
Colby, Kathryn A.
Kruse, Friedrich E.
author_sort Kinoshita, Shigeru
collection PubMed
description The current understanding on the clinical efficacy of Rho-associated protein kinase (ROCK) inhibitor for treating Fuchs endothelial corneal dystrophy is summarized to clarify whether the “off-label” ROCK-inhibitor eye-drop application are appropriate. ROCK-inhibitor eye drops may eventually be deemed a cutting-edge therapy for Fuchs endothelial corneal dystrophy patients with acute corneal endothelial defect.
format Online
Article
Text
id pubmed-8423139
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Cornea
record_format MEDLINE/PubMed
spelling pubmed-84231392021-09-13 A Close Look at the Clinical Efficacy of Rho-Associated Protein Kinase Inhibitor Eye Drops for Fuchs Endothelial Corneal Dystrophy Kinoshita, Shigeru Colby, Kathryn A. Kruse, Friedrich E. Cornea Invited Submission The current understanding on the clinical efficacy of Rho-associated protein kinase (ROCK) inhibitor for treating Fuchs endothelial corneal dystrophy is summarized to clarify whether the “off-label” ROCK-inhibitor eye-drop application are appropriate. ROCK-inhibitor eye drops may eventually be deemed a cutting-edge therapy for Fuchs endothelial corneal dystrophy patients with acute corneal endothelial defect. Cornea 2021-10 2021-02-03 /pmc/articles/PMC8423139/ /pubmed/34481406 http://dx.doi.org/10.1097/ICO.0000000000002642 Text en Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Invited Submission
Kinoshita, Shigeru
Colby, Kathryn A.
Kruse, Friedrich E.
A Close Look at the Clinical Efficacy of Rho-Associated Protein Kinase Inhibitor Eye Drops for Fuchs Endothelial Corneal Dystrophy
title A Close Look at the Clinical Efficacy of Rho-Associated Protein Kinase Inhibitor Eye Drops for Fuchs Endothelial Corneal Dystrophy
title_full A Close Look at the Clinical Efficacy of Rho-Associated Protein Kinase Inhibitor Eye Drops for Fuchs Endothelial Corneal Dystrophy
title_fullStr A Close Look at the Clinical Efficacy of Rho-Associated Protein Kinase Inhibitor Eye Drops for Fuchs Endothelial Corneal Dystrophy
title_full_unstemmed A Close Look at the Clinical Efficacy of Rho-Associated Protein Kinase Inhibitor Eye Drops for Fuchs Endothelial Corneal Dystrophy
title_short A Close Look at the Clinical Efficacy of Rho-Associated Protein Kinase Inhibitor Eye Drops for Fuchs Endothelial Corneal Dystrophy
title_sort close look at the clinical efficacy of rho-associated protein kinase inhibitor eye drops for fuchs endothelial corneal dystrophy
topic Invited Submission
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423139/
https://www.ncbi.nlm.nih.gov/pubmed/34481406
http://dx.doi.org/10.1097/ICO.0000000000002642
work_keys_str_mv AT kinoshitashigeru acloselookattheclinicalefficacyofrhoassociatedproteinkinaseinhibitoreyedropsforfuchsendothelialcornealdystrophy
AT colbykathryna acloselookattheclinicalefficacyofrhoassociatedproteinkinaseinhibitoreyedropsforfuchsendothelialcornealdystrophy
AT krusefriedriche acloselookattheclinicalefficacyofrhoassociatedproteinkinaseinhibitoreyedropsforfuchsendothelialcornealdystrophy
AT kinoshitashigeru closelookattheclinicalefficacyofrhoassociatedproteinkinaseinhibitoreyedropsforfuchsendothelialcornealdystrophy
AT colbykathryna closelookattheclinicalefficacyofrhoassociatedproteinkinaseinhibitoreyedropsforfuchsendothelialcornealdystrophy
AT krusefriedriche closelookattheclinicalefficacyofrhoassociatedproteinkinaseinhibitoreyedropsforfuchsendothelialcornealdystrophy

Ejemplares similares