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Epistasis at the SARS-CoV-2 RBD Interface and the Propitiously Boring Implications for Vaccine Escape

At the time of this writing, December 2021, potential emergence of vaccine escape variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a grave global concern. The interface between the receptor-binding domain (RBD) of SARS-CoV-2 spike (S) protein and the host receptor (ACE2) o...

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Detalles Bibliográficos
Autores principales: Rochman, Nash D., Faure, Guilhem, Wolf, Yuri I., Freddolino, Peter L., Zhang, Feng, Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423221/
https://www.ncbi.nlm.nih.gov/pubmed/34494024
http://dx.doi.org/10.1101/2021.08.30.458225