Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates

The development of an effective human immunodeficiency virus (HIV-1) vaccine is a high global health priority. Soluble native-like HIV-1 envelope glycoprotein trimers (Env), including those based on the SOSIP design, have shown promise as vaccine candidates by inducing neutralizing antibody response...

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Detalles Bibliográficos
Autores principales: van Schooten, Jelle, van Haaren, Marlies M., Li, Hui, McCoy, Laura E., Havenar-Daughton, Colin, Cottrell, Christopher A., Burger, Judith A., van der Woude, Patricia, Helgers, Leanne C., Tomris, Ilhan, Labranche, Celia C., Montefiori, David C., Ward, Andrew B., Burton, Dennis R., Moore, John P., Sanders, Rogier W., Crotty, Shane, Shaw, George M., van Gils, Marit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423243/
https://www.ncbi.nlm.nih.gov/pubmed/34432859
http://dx.doi.org/10.1371/journal.ppat.1009736

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