Beyond identity: Understanding the contribution of the 5’ nucleotide of the antisense strand to RNAi activity

In both the pharmaceutical and agricultural fields, RNA-based products have capitalized upon the mechanism of RNA interference for targeted reduction of gene expression to improve phenotypes and traits. Reduction in gene expression by RNAi is the result of a small interfering RNA (siRNA) molecule bi...

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Detalles Bibliográficos
Autores principales: Yang, Peizhen, Havecker, Ericka, Bauer, Matthew, Diehl, Carl, Hendrix, Bill, Hoffer, Paul, Boyle, Timothy, Bradley, John, Caruano-Yzermans, Amy, Deikman, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423273/
https://www.ncbi.nlm.nih.gov/pubmed/34492058
http://dx.doi.org/10.1371/journal.pone.0256863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423273/
https://www.ncbi.nlm.nih.gov/pubmed/34492058
http://dx.doi.org/10.1371/journal.pone.0256863

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