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Beyond identity: Understanding the contribution of the 5’ nucleotide of the antisense strand to RNAi activity
In both the pharmaceutical and agricultural fields, RNA-based products have capitalized upon the mechanism of RNA interference for targeted reduction of gene expression to improve phenotypes and traits. Reduction in gene expression by RNAi is the result of a small interfering RNA (siRNA) molecule bi...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423273/ https://www.ncbi.nlm.nih.gov/pubmed/34492058 http://dx.doi.org/10.1371/journal.pone.0256863 |