Principles of signaling pathway modulation for enhancing human naive pluripotency induction

Isolating human MEK/ERK signaling-independent pluripotent stem cells (PSCs) with naive pluripotency characteristics while maintaining differentiation competence and (epi)genetic integrity remains challenging. Here, we engineer reporter systems that allow the screening for defined conditions that ind...

Descripción completa

Detalles Bibliográficos
Autores principales: Bayerl, Jonathan, Ayyash, Muneef, Shani, Tom, Manor, Yair Shlomo, Gafni, Ohad, Massarwa, Rada, Kalma, Yael, Aguilera-Castrejon, Alejandro, Zerbib, Mirie, Amir, Hadar, Sheban, Daoud, Geula, Shay, Mor, Nofar, Weinberger, Leehee, Naveh Tassa, Segev, Krupalnik, Vladislav, Oldak, Bernardo, Livnat, Nir, Tarazi, Shadi, Tawil, Shadi, Wildschutz, Emilie, Ashouokhi, Shahd, Lasman, Lior, Rotter, Varda, Hanna, Suhair, Ben-Yosef, Dalit, Novershtern, Noa, Viukov, Sergey, Hanna, Jacob H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423434/
https://www.ncbi.nlm.nih.gov/pubmed/33915080
http://dx.doi.org/10.1016/j.stem.2021.04.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423434/
https://www.ncbi.nlm.nih.gov/pubmed/33915080
http://dx.doi.org/10.1016/j.stem.2021.04.001

Ejemplares similares