Infant Exposure to Dolutegravir Through Placental and Breast Milk Transfer: A Population Pharmacokinetic Analysis of DolPHIN-1

BACKGROUND: Rapid reduction in human immunodeficiency virus (HIV) load is paramount to prevent peripartum transmission in women diagnosed late in pregnancy. We investigated dolutegravir population pharmacokinetics in maternal plasma, umbilical cord, breast milk, and infant plasma samples from DolPHI...

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Detalles Bibliográficos
Autores principales: Dickinson, Laura, Walimbwa, Stephen, Singh, Yashna, Kaboggoza, Julian, Kintu, Kenneth, Sihlangu, Mary, Coombs, Julie-Anne, Malaba, Thokozile R, Byamugisha, Josaphat, Pertinez, Henry, Amara, Alieu, Gini, Joshua, Else, Laura, Heiberg, Christie, Hodel, Eva Maria, Reynolds, Helen, Myer, Landon, Waitt, Catriona, Khoo, Saye, Lamorde, Mohammed, Orrell, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Online Only Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423479/
https://www.ncbi.nlm.nih.gov/pubmed/33346335
http://dx.doi.org/10.1093/cid/ciaa1861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423479/
https://www.ncbi.nlm.nih.gov/pubmed/33346335
http://dx.doi.org/10.1093/cid/ciaa1861

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