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Evodiae fructus Extract Inhibits Interleukin-1β-Induced MMP-1, MMP-3, and Inflammatory Cytokine Expression by Suppressing the Activation of MAPK and STAT-3 in Human Gingival Fibroblasts In Vitro

Periodontitis is a Gram-negative bacterial infectious disease. Numerous inflammatory cytokines, including interleukin-1β (IL-1β), regulate periodontitis pathophysiology and cause periodontal tissue destruction. In human gingival fibroblasts (HGFs), IL-1β stimulates the production of matrix metallopr...

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Detalles Bibliográficos
Autores principales: Song, Hyun-Kyung, Noh, Eun-Mi, Kim, Jeong-Mi, You, Yong-Ouk, Kwon, Kang-Beom, Lee, Young-Rae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423542/
https://www.ncbi.nlm.nih.gov/pubmed/34504537
http://dx.doi.org/10.1155/2021/5858393