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Activation of the M3AChR and Notch1/HSF1 Signaling Pathway by Choline Alleviates Angiotensin II-Induced Cardiomyocyte Apoptosis
Angiotensin II- (Ang II-) induced cardiac hypertrophy and apoptosis are major characteristics of early-stage heart failure. Choline exerts cardioprotective effects; however, its effects on Ang II-induced cardiomyocyte apoptosis are unclear. In this study, the role and underlying mechanism of choline...
Autores principales: | Xu, Man, Bi, Xue-Yuan, Xue, Xiao-Rong, Lu, Xing-Zhu, Li, Qiong-Ge, Jian, Qiang, Sun, Jian-Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423579/ https://www.ncbi.nlm.nih.gov/pubmed/34504645 http://dx.doi.org/10.1155/2021/9979706 |
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