Aberrant Striatal Value Representation in Huntington's Disease Gene Carriers 25 Years Before Onset

BACKGROUND: In this study, we asked whether differences in striatal activity during a reinforcement learning (RL) task with gain and loss domains could be one of the earliest functional imaging features associated with carrying the Huntington's disease (HD) gene. Based on previous work, we hypo...

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Detalles Bibliográficos
Autores principales: Nair, Akshay, Johnson, Eileanoir B., Gregory, Sarah, Osborne-Crowley, Katherine, Zeun, Paul, Scahill, Rachael I., Lowe, Jessica, Papoutsi, Marina, Palminteri, Stefano, Rutledge, Robb B., Rees, Geraint, Tabrizi, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier, Inc 2021
Materias:
Archival Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423628/
https://www.ncbi.nlm.nih.gov/pubmed/33795209
http://dx.doi.org/10.1016/j.bpsc.2020.12.015

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