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The impact of maternal care and blood glucose availability on the cortisol stress response in fasted women
Individuals with a history of low maternal care (MC) frequently present a blunted, yet sometimes also show an increased cortisol stress response. Fasted individuals with low blood glucose levels who are exposed to acute stress typically show an attenuated response pattern in this endocrine marker. D...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423636/ https://www.ncbi.nlm.nih.gov/pubmed/33978833 http://dx.doi.org/10.1007/s00702-021-02350-y |
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author | Bentele, Ulrike U. Meier, Maria Benz, Annika B. E. Denk, Bernadette F. Dimitroff, Stephanie J. Pruessner, Jens C. Unternaehrer, Eva |
author_facet | Bentele, Ulrike U. Meier, Maria Benz, Annika B. E. Denk, Bernadette F. Dimitroff, Stephanie J. Pruessner, Jens C. Unternaehrer, Eva |
author_sort | Bentele, Ulrike U. |
collection | PubMed |
description | Individuals with a history of low maternal care (MC) frequently present a blunted, yet sometimes also show an increased cortisol stress response. Fasted individuals with low blood glucose levels who are exposed to acute stress typically show an attenuated response pattern in this endocrine marker. Despite well-documented metabolic dysregulations after low MC, a possible interaction of both factors has not been investigated yet. Here, we examined the effects of MC and blood glucose concentration on various aspects of the stress response. Fasted women (N = 122, mean(age) = 22.12, sd(age) = 2.56) who experienced either very high, high, or low MC (based on the Parental Bonding Instrument) were randomly assigned to consume grape juice (condition sugar), or water (condition water) prior to being exposed to the Trier-Social-Stress-Test for groups. Salivary cortisol and alpha amylase, blood glucose, and mood ratings were assessed repeatedly. Using multilevel mixed models, we replicated the boosting effect of glucose on the cortisol stress response. While we found neither an effect of MC, nor an interaction between MC and blood glucose availability on the cortisol stress response, we observed an effect of MC on the amylase stress response. We discuss the results in the light of links between various stress/energy systems that possibly mediate health-related MC effects. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00702-021-02350-y. |
format | Online Article Text |
id | pubmed-8423636 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Vienna |
record_format | MEDLINE/PubMed |
spelling | pubmed-84236362021-09-09 The impact of maternal care and blood glucose availability on the cortisol stress response in fasted women Bentele, Ulrike U. Meier, Maria Benz, Annika B. E. Denk, Bernadette F. Dimitroff, Stephanie J. Pruessner, Jens C. Unternaehrer, Eva J Neural Transm (Vienna) Psychiatry and Preclinical Psychiatric Studies - Original Article Individuals with a history of low maternal care (MC) frequently present a blunted, yet sometimes also show an increased cortisol stress response. Fasted individuals with low blood glucose levels who are exposed to acute stress typically show an attenuated response pattern in this endocrine marker. Despite well-documented metabolic dysregulations after low MC, a possible interaction of both factors has not been investigated yet. Here, we examined the effects of MC and blood glucose concentration on various aspects of the stress response. Fasted women (N = 122, mean(age) = 22.12, sd(age) = 2.56) who experienced either very high, high, or low MC (based on the Parental Bonding Instrument) were randomly assigned to consume grape juice (condition sugar), or water (condition water) prior to being exposed to the Trier-Social-Stress-Test for groups. Salivary cortisol and alpha amylase, blood glucose, and mood ratings were assessed repeatedly. Using multilevel mixed models, we replicated the boosting effect of glucose on the cortisol stress response. While we found neither an effect of MC, nor an interaction between MC and blood glucose availability on the cortisol stress response, we observed an effect of MC on the amylase stress response. We discuss the results in the light of links between various stress/energy systems that possibly mediate health-related MC effects. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00702-021-02350-y. Springer Vienna 2021-05-12 2021 /pmc/articles/PMC8423636/ /pubmed/33978833 http://dx.doi.org/10.1007/s00702-021-02350-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Psychiatry and Preclinical Psychiatric Studies - Original Article Bentele, Ulrike U. Meier, Maria Benz, Annika B. E. Denk, Bernadette F. Dimitroff, Stephanie J. Pruessner, Jens C. Unternaehrer, Eva The impact of maternal care and blood glucose availability on the cortisol stress response in fasted women |
title | The impact of maternal care and blood glucose availability on the cortisol stress response in fasted women |
title_full | The impact of maternal care and blood glucose availability on the cortisol stress response in fasted women |
title_fullStr | The impact of maternal care and blood glucose availability on the cortisol stress response in fasted women |
title_full_unstemmed | The impact of maternal care and blood glucose availability on the cortisol stress response in fasted women |
title_short | The impact of maternal care and blood glucose availability on the cortisol stress response in fasted women |
title_sort | impact of maternal care and blood glucose availability on the cortisol stress response in fasted women |
topic | Psychiatry and Preclinical Psychiatric Studies - Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423636/ https://www.ncbi.nlm.nih.gov/pubmed/33978833 http://dx.doi.org/10.1007/s00702-021-02350-y |
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