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SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players
There is increasing evidence of cardiac involvement post-SARS-CoV-2 infections in symptomatic as well as in oligo- and asymptomatic athletes. This study aimed to characterize the possible early effects of SARS-CoV-2 infections on myocardial morphology and cardiopulmonary function in athletes. Eight...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423785/ https://www.ncbi.nlm.nih.gov/pubmed/34493765 http://dx.doi.org/10.1038/s41598-021-97120-x |
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author | Fikenzer, S. Kogel, A. Pietsch, C. Lavall, D. Stöbe, St. Rudolph, U. Laufs, U. Hepp, P. Hagendorff, A. |
author_facet | Fikenzer, S. Kogel, A. Pietsch, C. Lavall, D. Stöbe, St. Rudolph, U. Laufs, U. Hepp, P. Hagendorff, A. |
author_sort | Fikenzer, S. |
collection | PubMed |
description | There is increasing evidence of cardiac involvement post-SARS-CoV-2 infections in symptomatic as well as in oligo- and asymptomatic athletes. This study aimed to characterize the possible early effects of SARS-CoV-2 infections on myocardial morphology and cardiopulmonary function in athletes. Eight male elite handball players (27 ± 3.5 y) with past SARS-CoV-2 infection were compared with four uninfected teammates (22 ± 2.6 y). Infected athletes were examined 19 ± 7 days after the first positive PCR test. Echocardiographic assessment of the global longitudinal strain under resting conditions was not significantly changed (− 17.7% vs. − 18.1%). However, magnetic resonance imaging showed minor signs of acute inflammation/oedema in all infected athletes (T2-mapping: + 4.1 ms, p = 0.034) without reaching the Lake-Louis criteria. Spiroergometric analysis showed a significant reduction in VO2max (− 292 ml/min, − 7.0%), oxygen pulse (− 2.4 ml/beat, − 10.4%), and respiratory minute volume (VE) (− 18.9 l/min, − 13.8%) in athletes with a history of SARS-CoV2 infection (p < 0.05, respectively). The parameters were unchanged in the uninfected teammates. SARS-CoV2 infection caused impairment of cardiopulmonary performance during physical effort in elite athletes. It seems reasonable to screen athletes after SARS-CoV2 infection with spiroergometry to identify performance limitations and to guide the return to competition. |
format | Online Article Text |
id | pubmed-8423785 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-84237852021-09-09 SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players Fikenzer, S. Kogel, A. Pietsch, C. Lavall, D. Stöbe, St. Rudolph, U. Laufs, U. Hepp, P. Hagendorff, A. Sci Rep Article There is increasing evidence of cardiac involvement post-SARS-CoV-2 infections in symptomatic as well as in oligo- and asymptomatic athletes. This study aimed to characterize the possible early effects of SARS-CoV-2 infections on myocardial morphology and cardiopulmonary function in athletes. Eight male elite handball players (27 ± 3.5 y) with past SARS-CoV-2 infection were compared with four uninfected teammates (22 ± 2.6 y). Infected athletes were examined 19 ± 7 days after the first positive PCR test. Echocardiographic assessment of the global longitudinal strain under resting conditions was not significantly changed (− 17.7% vs. − 18.1%). However, magnetic resonance imaging showed minor signs of acute inflammation/oedema in all infected athletes (T2-mapping: + 4.1 ms, p = 0.034) without reaching the Lake-Louis criteria. Spiroergometric analysis showed a significant reduction in VO2max (− 292 ml/min, − 7.0%), oxygen pulse (− 2.4 ml/beat, − 10.4%), and respiratory minute volume (VE) (− 18.9 l/min, − 13.8%) in athletes with a history of SARS-CoV2 infection (p < 0.05, respectively). The parameters were unchanged in the uninfected teammates. SARS-CoV2 infection caused impairment of cardiopulmonary performance during physical effort in elite athletes. It seems reasonable to screen athletes after SARS-CoV2 infection with spiroergometry to identify performance limitations and to guide the return to competition. Nature Publishing Group UK 2021-09-07 /pmc/articles/PMC8423785/ /pubmed/34493765 http://dx.doi.org/10.1038/s41598-021-97120-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Fikenzer, S. Kogel, A. Pietsch, C. Lavall, D. Stöbe, St. Rudolph, U. Laufs, U. Hepp, P. Hagendorff, A. SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players |
title | SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players |
title_full | SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players |
title_fullStr | SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players |
title_full_unstemmed | SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players |
title_short | SARS-CoV2 infection: functional and morphological cardiopulmonary changes in elite handball players |
title_sort | sars-cov2 infection: functional and morphological cardiopulmonary changes in elite handball players |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423785/ https://www.ncbi.nlm.nih.gov/pubmed/34493765 http://dx.doi.org/10.1038/s41598-021-97120-x |
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