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Increased NKX6.1 expression and decreased ARX expression in alpha cells accompany reduced beta-cell volume in human subjects

Pancreatic islet cells have plasticity, such as the abilities to dedifferentiate and transdifferentiate. Islet cell conversion to other characteristic cell is largely determined by transcription factors, but significance of expression patterns of these transcription factors in human islet cells rema...

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Detalles Bibliográficos
Autores principales:	Fujita, Yukari, Kozawa, Junji, Fukui, Kenji, Iwahashi, Hiromi, Eguchi, Hidetoshi, Shimomura, Iichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423790/ https://www.ncbi.nlm.nih.gov/pubmed/34493754 http://dx.doi.org/10.1038/s41598-021-97235-1

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