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Tianeptine modulates synaptic vesicle dynamics and favors synaptic mitochondria processes in socially isolated rats

Deregulation of synaptic function and neurotransmission has been linked with the development of major depression disorder (MDD). Tianeptine (Tian) has been used as antidepressant with anxiolytic properties and recently as a nootropic to improve cognitive performance, but its mechanism of action is u...

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Detalles Bibliográficos
Autores principales: Perić, Ivana, Costina, Victor, Djordjević, Snežana, Gass, Peter, Findeisen, Peter, Inta, Dragoš, Borgwardt, Stefan, Filipović, Dragana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423821/
https://www.ncbi.nlm.nih.gov/pubmed/34493757
http://dx.doi.org/10.1038/s41598-021-97186-7

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