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Tianeptine modulates synaptic vesicle dynamics and favors synaptic mitochondria processes in socially isolated rats
Deregulation of synaptic function and neurotransmission has been linked with the development of major depression disorder (MDD). Tianeptine (Tian) has been used as antidepressant with anxiolytic properties and recently as a nootropic to improve cognitive performance, but its mechanism of action is u...
Autores principales: | Perić, Ivana, Costina, Victor, Djordjević, Snežana, Gass, Peter, Findeisen, Peter, Inta, Dragoš, Borgwardt, Stefan, Filipović, Dragana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423821/ https://www.ncbi.nlm.nih.gov/pubmed/34493757 http://dx.doi.org/10.1038/s41598-021-97186-7 |
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