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Ferulic Acid Ameliorates Alzheimer’s Disease-like Pathology and Repairs Cognitive Decline by Preventing Capillary Hypofunction in APP/PS1 Mice
Brain capillaries are crucial for cognitive functions by supplying oxygen and other nutrients to and removing metabolic wastes from the brain. Recent studies have demonstrated that constriction of brain capillaries is triggered by beta-amyloid (Aβ) oligomers via endothelin-1 (ET1)-mediated action on...
Autores principales: | Wang, Ni-Ya, Li, Jin-Nan, Liu, Wei-Lin, Huang, Qi, Li, Wen-Xing, Tan, Ya-Hong, Liu, Fang, Song, Zi-Hua, Wang, Meng-Yue, Xie, Ning, Mao, Rong-Rong, Gan, Ping, Ding, Yu-Qiang, Zhang, Zhi, Shan, Bao-Ci, Chen, Li-Dian, Zhou, Qi-Xin, Xu, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423929/ https://www.ncbi.nlm.nih.gov/pubmed/33786807 http://dx.doi.org/10.1007/s13311-021-01024-7 |
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