Myocardial T(1)-mapping and Extracellular Volume Quantification in Patients and Putative Carriers of Muscular Dystrophy: Early Experience

To assess myocardial fibrosis associated with muscular dystrophy, T(1)-mapping and extracellular volume fraction (ECV) quantification was prospectively performed using cardiovascular MR (CMR) imaging in 6 male patients with muscular dystrophy and 5 female putative carriers of Duchenne or Becker musc...

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Detalles Bibliográficos
Autores principales: Koyanagawa, Kazuhiro, Kobayashi, Yuta, Aikawa, Tadao, Takeda, Atsuhito, Shiraishi, Hideaki, Tsuneta, Satonori, Oyama-Manabe, Noriko, Iwano, Hiroyuki, Nagai, Toshiyuki, Anzai, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Magnetic Resonance in Medicine 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424027/
https://www.ncbi.nlm.nih.gov/pubmed/32893256
http://dx.doi.org/10.2463/mrms.bc.2020-0069
Descripción
Sumario:To assess myocardial fibrosis associated with muscular dystrophy, T(1)-mapping and extracellular volume fraction (ECV) quantification was prospectively performed using cardiovascular MR (CMR) imaging in 6 male patients with muscular dystrophy and 5 female putative carriers of Duchenne or Becker muscular dystrophy. Five patients and all putative carriers had an elevated ECV (>29.5% for men and >35.2% for women), suggesting that ECV has a potential to detect diffuse fibrotic changes in patients and putative carriers of muscular dystrophy.

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