Myocardial T(1)-mapping and Extracellular Volume Quantification in Patients and Putative Carriers of Muscular Dystrophy: Early Experience

To assess myocardial fibrosis associated with muscular dystrophy, T(1)-mapping and extracellular volume fraction (ECV) quantification was prospectively performed using cardiovascular MR (CMR) imaging in 6 male patients with muscular dystrophy and 5 female putative carriers of Duchenne or Becker musc...

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Autores principales: Koyanagawa, Kazuhiro, Kobayashi, Yuta, Aikawa, Tadao, Takeda, Atsuhito, Shiraishi, Hideaki, Tsuneta, Satonori, Oyama-Manabe, Noriko, Iwano, Hiroyuki, Nagai, Toshiyuki, Anzai, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Magnetic Resonance in Medicine 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424027/
https://www.ncbi.nlm.nih.gov/pubmed/32893256
http://dx.doi.org/10.2463/mrms.bc.2020-0069
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author Koyanagawa, Kazuhiro
Kobayashi, Yuta
Aikawa, Tadao
Takeda, Atsuhito
Shiraishi, Hideaki
Tsuneta, Satonori
Oyama-Manabe, Noriko
Iwano, Hiroyuki
Nagai, Toshiyuki
Anzai, Toshihisa
author_facet Koyanagawa, Kazuhiro
Kobayashi, Yuta
Aikawa, Tadao
Takeda, Atsuhito
Shiraishi, Hideaki
Tsuneta, Satonori
Oyama-Manabe, Noriko
Iwano, Hiroyuki
Nagai, Toshiyuki
Anzai, Toshihisa
author_sort Koyanagawa, Kazuhiro
collection PubMed
description To assess myocardial fibrosis associated with muscular dystrophy, T(1)-mapping and extracellular volume fraction (ECV) quantification was prospectively performed using cardiovascular MR (CMR) imaging in 6 male patients with muscular dystrophy and 5 female putative carriers of Duchenne or Becker muscular dystrophy. Five patients and all putative carriers had an elevated ECV (>29.5% for men and >35.2% for women), suggesting that ECV has a potential to detect diffuse fibrotic changes in patients and putative carriers of muscular dystrophy.
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spelling pubmed-84240272021-09-24 Myocardial T(1)-mapping and Extracellular Volume Quantification in Patients and Putative Carriers of Muscular Dystrophy: Early Experience Koyanagawa, Kazuhiro Kobayashi, Yuta Aikawa, Tadao Takeda, Atsuhito Shiraishi, Hideaki Tsuneta, Satonori Oyama-Manabe, Noriko Iwano, Hiroyuki Nagai, Toshiyuki Anzai, Toshihisa Magn Reson Med Sci Brief Communication To assess myocardial fibrosis associated with muscular dystrophy, T(1)-mapping and extracellular volume fraction (ECV) quantification was prospectively performed using cardiovascular MR (CMR) imaging in 6 male patients with muscular dystrophy and 5 female putative carriers of Duchenne or Becker muscular dystrophy. Five patients and all putative carriers had an elevated ECV (>29.5% for men and >35.2% for women), suggesting that ECV has a potential to detect diffuse fibrotic changes in patients and putative carriers of muscular dystrophy. Japanese Society for Magnetic Resonance in Medicine 2020-09-07 /pmc/articles/PMC8424027/ /pubmed/32893256 http://dx.doi.org/10.2463/mrms.bc.2020-0069 Text en © 2021 Japanese Society for Magnetic Resonance in Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Brief Communication
Koyanagawa, Kazuhiro
Kobayashi, Yuta
Aikawa, Tadao
Takeda, Atsuhito
Shiraishi, Hideaki
Tsuneta, Satonori
Oyama-Manabe, Noriko
Iwano, Hiroyuki
Nagai, Toshiyuki
Anzai, Toshihisa
Myocardial T(1)-mapping and Extracellular Volume Quantification in Patients and Putative Carriers of Muscular Dystrophy: Early Experience
title Myocardial T(1)-mapping and Extracellular Volume Quantification in Patients and Putative Carriers of Muscular Dystrophy: Early Experience
title_full Myocardial T(1)-mapping and Extracellular Volume Quantification in Patients and Putative Carriers of Muscular Dystrophy: Early Experience
title_fullStr Myocardial T(1)-mapping and Extracellular Volume Quantification in Patients and Putative Carriers of Muscular Dystrophy: Early Experience
title_full_unstemmed Myocardial T(1)-mapping and Extracellular Volume Quantification in Patients and Putative Carriers of Muscular Dystrophy: Early Experience
title_short Myocardial T(1)-mapping and Extracellular Volume Quantification in Patients and Putative Carriers of Muscular Dystrophy: Early Experience
title_sort myocardial t(1)-mapping and extracellular volume quantification in patients and putative carriers of muscular dystrophy: early experience
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424027/
https://www.ncbi.nlm.nih.gov/pubmed/32893256
http://dx.doi.org/10.2463/mrms.bc.2020-0069
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