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Efficiency and Safety of the Selective Relaxant Binding Agent Adamgammadex Sodium for Reversing Rocuronium-Induced Deep Neuromuscular Block: A Single-Center, Open-Label, Dose-Finding, and Phase IIa Study

Background: Rapid reversal of neuromuscular block after surgery and anesthesia is often necessary. Here, we reported the primary efficacy and safety data from a phase IIa study on adamgammadex sodium, a newly developed modified γ-cyclodextrin derivative. Methods: This was a phase IIa, single-center,...

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Detalles Bibliográficos
Autores principales: Zhao, Yanhua, Chen, Sifan, Huai, Xiaorong, Yu, Zhangjie, Qi, Youmiao, Qing, Jie, Yu, Weifeng, Su, Diansan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424042/
https://www.ncbi.nlm.nih.gov/pubmed/34513870
http://dx.doi.org/10.3389/fmed.2021.697395