Retinoid Metabolism in the Degeneration of Pten-Deficient Mouse Retinal Pigment Epithelium

In vertebrate eyes, the retinal pigment epithelium (RPE) provides structural and functional homeostasis to the retina. The RPE takes up retinol (ROL) to be dehydrogenated and isomerized to 11-cis-retinaldehyde (11-cis-RAL), which is a functional photopigment in mammalian photoreceptors. As excessive...

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Detalles Bibliográficos
Autores principales: Kim, You-Joung, Park, Sooyeon, Ha, Taejeong, Kim, Seungbeom, Lim, Soyeon, You, Han, Kim, Jin Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424139/
https://www.ncbi.nlm.nih.gov/pubmed/34376625
http://dx.doi.org/10.14348/molcells.2021.0138

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