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First diagnosis of multisystem inflammatory syndrome in children (MIS-C): an analysis of PoCUS findings in the ED
Children with multisystem inflammatory syndrome (MIS-C) tend to develop a clinical condition of fluid overload due both to contractile cardiac pump deficit and to endotheliitis with subsequent capillary leak syndrome. In this context, the ability of point-of-care ultrasound (PoCUS) to simultaneously...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424151/ https://www.ncbi.nlm.nih.gov/pubmed/34495434 http://dx.doi.org/10.1186/s13089-021-00243-5 |
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author | Delmonaco, Angelo G. Carpino, Andrea Raffaldi, Irene Pruccoli, Giulia Garrone, Emanuela Del Monte, Francesco Riboldi, Lorenzo Licciardi, Francesco Urbino, Antonio F. Parodi, Emilia |
author_facet | Delmonaco, Angelo G. Carpino, Andrea Raffaldi, Irene Pruccoli, Giulia Garrone, Emanuela Del Monte, Francesco Riboldi, Lorenzo Licciardi, Francesco Urbino, Antonio F. Parodi, Emilia |
author_sort | Delmonaco, Angelo G. |
collection | PubMed |
description | Children with multisystem inflammatory syndrome (MIS-C) tend to develop a clinical condition of fluid overload due both to contractile cardiac pump deficit and to endotheliitis with subsequent capillary leak syndrome. In this context, the ability of point-of-care ultrasound (PoCUS) to simultaneously explore multiple systems and detect polyserositis could promote adequate therapeutic management of fluid balance. We describe the PoCUS findings in a case-series of MIS-C patients admitted to the Emergency Department. At admission 10/11 patients showed satisfactory clinical condition without signs and symptoms suggestive for cardiovascular impairment/shock, but PoCUS showed pathological findings in 11/11 (100%). In particular, according to Rapid Ultrasound in SHock (RUSH) protocol, cardiac hypokinesis was detected in 5/11 (45%) and inferior vena cava dilatation in 3/11 (27%). Peritoneal fluid was reported in 6/11 cases (54%). Lung ultrasound (LUS) evaluation revealed an interstitial syndrome in 11/11 (100%), mainly localized in posterior basal lung segments. We suggest PoCUS as a useful tool in the first evaluation of children with suspected MIS-C for the initial therapeutic management and the following monitoring of possible cardiovascular deterioration. |
format | Online Article Text |
id | pubmed-8424151 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-84241512021-09-08 First diagnosis of multisystem inflammatory syndrome in children (MIS-C): an analysis of PoCUS findings in the ED Delmonaco, Angelo G. Carpino, Andrea Raffaldi, Irene Pruccoli, Giulia Garrone, Emanuela Del Monte, Francesco Riboldi, Lorenzo Licciardi, Francesco Urbino, Antonio F. Parodi, Emilia Ultrasound J Short Communication Children with multisystem inflammatory syndrome (MIS-C) tend to develop a clinical condition of fluid overload due both to contractile cardiac pump deficit and to endotheliitis with subsequent capillary leak syndrome. In this context, the ability of point-of-care ultrasound (PoCUS) to simultaneously explore multiple systems and detect polyserositis could promote adequate therapeutic management of fluid balance. We describe the PoCUS findings in a case-series of MIS-C patients admitted to the Emergency Department. At admission 10/11 patients showed satisfactory clinical condition without signs and symptoms suggestive for cardiovascular impairment/shock, but PoCUS showed pathological findings in 11/11 (100%). In particular, according to Rapid Ultrasound in SHock (RUSH) protocol, cardiac hypokinesis was detected in 5/11 (45%) and inferior vena cava dilatation in 3/11 (27%). Peritoneal fluid was reported in 6/11 cases (54%). Lung ultrasound (LUS) evaluation revealed an interstitial syndrome in 11/11 (100%), mainly localized in posterior basal lung segments. We suggest PoCUS as a useful tool in the first evaluation of children with suspected MIS-C for the initial therapeutic management and the following monitoring of possible cardiovascular deterioration. Springer International Publishing 2021-09-08 /pmc/articles/PMC8424151/ /pubmed/34495434 http://dx.doi.org/10.1186/s13089-021-00243-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Short Communication Delmonaco, Angelo G. Carpino, Andrea Raffaldi, Irene Pruccoli, Giulia Garrone, Emanuela Del Monte, Francesco Riboldi, Lorenzo Licciardi, Francesco Urbino, Antonio F. Parodi, Emilia First diagnosis of multisystem inflammatory syndrome in children (MIS-C): an analysis of PoCUS findings in the ED |
title | First diagnosis of multisystem inflammatory syndrome in children (MIS-C): an analysis of PoCUS findings in the ED |
title_full | First diagnosis of multisystem inflammatory syndrome in children (MIS-C): an analysis of PoCUS findings in the ED |
title_fullStr | First diagnosis of multisystem inflammatory syndrome in children (MIS-C): an analysis of PoCUS findings in the ED |
title_full_unstemmed | First diagnosis of multisystem inflammatory syndrome in children (MIS-C): an analysis of PoCUS findings in the ED |
title_short | First diagnosis of multisystem inflammatory syndrome in children (MIS-C): an analysis of PoCUS findings in the ED |
title_sort | first diagnosis of multisystem inflammatory syndrome in children (mis-c): an analysis of pocus findings in the ed |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424151/ https://www.ncbi.nlm.nih.gov/pubmed/34495434 http://dx.doi.org/10.1186/s13089-021-00243-5 |
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