Cargando…

The Regulatory Role of GBF1 on Osteoclast Activation Through EIF2a Mediated ER Stress and Novel Marker FAM129A Induction

Bone-resorbing activities of osteoclasts (OCs) are highly dependent on actin cytoskeleton remodeling, plasma membrane reorganization, and vesicle trafficking pathways, which are partially regulated by ARF-GTPases. In the present study, the functional roles of Golgi brefeldin A resistance factor 1 (G...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wen, Cailing, Zhou, Yuheng, Xu, Yanting, Tan, Huijing, Pang, Caixia, Liu, Haiqian, Liu, Kaifei, Wei, Linlin, Luo, Hui, Qin, Tian, He, Chonghua, Liu, Cuiling, Zhou, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424197/ https://www.ncbi.nlm.nih.gov/pubmed/34513838 http://dx.doi.org/10.3389/fcell.2021.706768

Ejemplares similares

A GBF1-Dependent Mechanism for Environmentally Responsive Regulation of ER-Golgi Transport
por: Lopes-da-Silva, Mafalda, et al.
Publicado: (2019)

The ArfGEF GBF-1 Is Required for ER Structure, Secretion and Endocytic Transport in C. elegans
por: Ackema, Karin B., et al.
Publicado: (2013)

Site-specific phosphorylations of the Arf activator GBF1 differentially regulate GBF1 function in Golgi homeostasis and secretion versus cytokinesis
por: Walton, Kendall, et al.
Publicado: (2023)

CSFV proliferation is associated with GBF1 and Rab2
por: Liang, Wulong, et al.
Publicado: (2016)

FAM134B-mediated ER-phagy regulates ER-mitochondria interaction through MAMs: FAM134B-mediated ER-phagy regulates ER-mitochondria interaction
por: Chen, Wei, et al.
Publicado: (2021)

FAM69C functions as a kinase for eIF2α and promotes stress granule assembly
por: Wu, Zhongyan, et al.
Publicado: (2023)

eIF2α signaling regulates autophagy of osteoblasts and the development of osteoclasts in OVX mice
por: Li, Jie, et al.
Publicado: (2019)

GBF3 transcription factor imparts drought tolerance in Arabidopsis thaliana
por: Ramegowda, Venkategowda, et al.
Publicado: (2017)

Src activates retrograde membrane traffic through phosphorylation of GBF1
por: Chia, Joanne, et al.
Publicado: (2021)

FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells
por: Conrad, Willliam, et al.
Publicado: (2013)

FAM129B, an antioxidative protein, reduces chemosensitivity by competing with Nrf2 for Keap1 binding
por: Cheng, Kai-Chun, et al.
Publicado: (2019)

SNPs in SNCA, MCCC1, DLG2, GBF1 and MBNL2 are associated with Parkinson's disease in southern Chinese population
por: Zhao, Aonan, et al.
Publicado: (2020)

Critical roles of FAM134B in ER-phagy and diseases
por: Mo, Jie, et al.
Publicado: (2020)

Interaction between the Triglyceride Lipase ATGL and the Arf1 Activator GBF1
por: Ellong, Emy Njoh, et al.
Publicado: (2011)

Golgicide A reveals essential roles for GBF1 in Golgi assembly and function
por: Saenz, Jose B., et al.
Publicado: (2009)

Role of the Guanine Nucleotide Exchange Factor GBF1 in the Replication of RNA Viruses
por: Martínez, José L., et al.
Publicado: (2020)

MiR-142-5p/FAM134B Axis Manipulates ER-Phagy to Control PRRSV Replication
por: Guan, Kaifeng, et al.
Publicado: (2022)

FAM129A promotes self-renewal and maintains invasive status via stabilizing the Notch intracellular domain in glioma stem cells
por: Liu, Guohao, et al.
Publicado: (2023)

Beating the ER: novel insights into FAM134B function and regulation
por: De Leonibus, Chiara, et al.
Publicado: (2020)

GBF1 and Arf1 interact with Miro and regulate mitochondrial positioning within cells
por: Walch, Laurence, et al.
Publicado: (2018)

CircFam190a: a critical positive regulator of osteoclast differentiation via enhancement of the AKT1/HSP90β complex
por: Chen, Kun, et al.
Publicado: (2023)

Climacocystaceae fam. nov. and Gloeoporellaceae fam. nov., two new families of Polyporales (Basidiomycota)
por: Liu, Shun, et al.
Publicado: (2023)

AG1478 Elicits a Novel Anti-Influenza Function via an EGFR-Independent, GBF1-Dependent Pathway
por: Zhou, Xu, et al.
Publicado: (2022)

Implication of KRT16, FAM129A and HKDC1 genes as ATF4 regulated components of the integrated stress response
por: Evstafieva, Alexandra G., et al.
Publicado: (2018)

Adipose-derived stem cell exosomes regulate Nrf2/Keap1 in diabetic nephropathy by targeting FAM129B
por: Ren, Peiyao, et al.
Publicado: (2023)

Mouse Hepatitis Coronavirus RNA Replication Depends on GBF1-Mediated ARF1 Activation
por: Verheije, Monique H., et al.
Publicado: (2008)

Phosphorylation Affects DNA-Binding of the Senescence-Regulating bZIP Transcription Factor GBF1
por: Smykowski, Anja, et al.
Publicado: (2015)

De Novo and Inherited Variants in GBF1 are Associated with Axonal Neuropathy Caused by Golgi Fragmentation
por: Mendoza-Ferreira, Natalia, et al.
Publicado: (2020)

Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality
por: Navare, Arti T, et al.
Publicado: (2020)

Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality
por: Navare, Arti T., et al.
Publicado: (2022)

The Arf-GEF GBF1 undergoes multi-domain structural shifts to activate Arf at the Golgi
por: Meissner, Justyna M., et al.
Publicado: (2023)

FAM20A Mutations Can Cause Enamel-Renal Syndrome (ERS)
por: Wang, Shih-Kai, et al.
Publicado: (2013)

MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A
por: Ayesha, Munawar, et al.
Publicado: (2021)

An N-terminal–truncated isoform of FAM134B (FAM134B-2) regulates starvation-induced hepatic selective ER-phagy
por: Kohno, Shohei, et al.
Publicado: (2019)

LncRNA FAM181A-AS1 promotes gliomagenesis by sponging miR-129-5p and upregulating ZRANB2
por: Jiang, Xin, et al.
Publicado: (2020)

A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy
por: Wang, Xinyi, et al.
Publicado: (2023)

Poliovirus replication requires the N‐terminus but not the catalytic Sec7 domain of ArfGEF GBF1
por: Belov, George A., et al.
Publicado: (2010)

GBF/Gea mutant with a single substitution sustains fungal growth in the absence of BIG/Sec7
por: Arst, Herbert N., et al.
Publicado: (2014)

Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy
por: Di Lorenzo, Giorgia, et al.
Publicado: (2022)

Inhibitors of eIF4G1–eIF1 uncover its regulatory role of ER/UPR stress-response genes independent of eIF2α-phosphorylation
por: Sehrawat, Urmila, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h11c72djd4p5npn8tamrk6mikf