Adverse Cardiovascular Effects of Anti-COVID-19 Drugs

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or COVID-19 infection is the cause of the ongoing global pandemic. Mortality from COVID-19 infection is particularly high in patients with cardiovascular diseases. In addition, COVID-19 patients with preexisting cardiovascular comorbiditie...

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Autores principales: Liu, Dongling, Zeng, Xiang, Ding, Zufeng, Lv, Fenghua, Mehta, Jawahar L., Wang, Xianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424204/
https://www.ncbi.nlm.nih.gov/pubmed/34512335
http://dx.doi.org/10.3389/fphar.2021.699949
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author Liu, Dongling
Zeng, Xiang
Ding, Zufeng
Lv, Fenghua
Mehta, Jawahar L.
Wang, Xianwei
author_facet Liu, Dongling
Zeng, Xiang
Ding, Zufeng
Lv, Fenghua
Mehta, Jawahar L.
Wang, Xianwei
author_sort Liu, Dongling
collection PubMed
description Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or COVID-19 infection is the cause of the ongoing global pandemic. Mortality from COVID-19 infection is particularly high in patients with cardiovascular diseases. In addition, COVID-19 patients with preexisting cardiovascular comorbidities have a higher risk of death. Main cardiovascular complications of COVID-19 are myocardial infarction, myocarditis, acute myocardial injury, arrhythmias, heart failure, stroke, and venous thromboembolism. Therapeutic interventions in terms of drugs for COVID-19 have many cardiac adverse effects. Here, we review the relative therapeutic efficacy and adverse effects of anti-COVID-19 drugs.
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spelling pubmed-84242042021-09-09 Adverse Cardiovascular Effects of Anti-COVID-19 Drugs Liu, Dongling Zeng, Xiang Ding, Zufeng Lv, Fenghua Mehta, Jawahar L. Wang, Xianwei Front Pharmacol Pharmacology Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or COVID-19 infection is the cause of the ongoing global pandemic. Mortality from COVID-19 infection is particularly high in patients with cardiovascular diseases. In addition, COVID-19 patients with preexisting cardiovascular comorbidities have a higher risk of death. Main cardiovascular complications of COVID-19 are myocardial infarction, myocarditis, acute myocardial injury, arrhythmias, heart failure, stroke, and venous thromboembolism. Therapeutic interventions in terms of drugs for COVID-19 have many cardiac adverse effects. Here, we review the relative therapeutic efficacy and adverse effects of anti-COVID-19 drugs. Frontiers Media S.A. 2021-08-25 /pmc/articles/PMC8424204/ /pubmed/34512335 http://dx.doi.org/10.3389/fphar.2021.699949 Text en Copyright © 2021 Liu, Zeng, Ding, Lv, Mehta and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Liu, Dongling
Zeng, Xiang
Ding, Zufeng
Lv, Fenghua
Mehta, Jawahar L.
Wang, Xianwei
Adverse Cardiovascular Effects of Anti-COVID-19 Drugs
title Adverse Cardiovascular Effects of Anti-COVID-19 Drugs
title_full Adverse Cardiovascular Effects of Anti-COVID-19 Drugs
title_fullStr Adverse Cardiovascular Effects of Anti-COVID-19 Drugs
title_full_unstemmed Adverse Cardiovascular Effects of Anti-COVID-19 Drugs
title_short Adverse Cardiovascular Effects of Anti-COVID-19 Drugs
title_sort adverse cardiovascular effects of anti-covid-19 drugs
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424204/
https://www.ncbi.nlm.nih.gov/pubmed/34512335
http://dx.doi.org/10.3389/fphar.2021.699949
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