Lipidated peptides derived from intracellular loops 2 and 3 of the urotensin II receptor act as biased allosteric ligands

Over the last decade, the urotensinergic system, composed of one G protein-coupled receptor and two endogenous ligands, has garnered significant attention as a promising new target for the treatment of various cardiovascular diseases. Indeed, this system is associated with various biomarkers of card...

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Detalles Bibliográficos
Autores principales: Nassour, Hassan, Hoang, Tuan Anh, Martin, Ryan D., Dallagnol, Juliana C.C., Billard, Étienne, Létourneau, Myriam, Novellino, Ettore, Carotenuto, Alfonso, Allen, Bruce G., Tanny, Jason C., Fournier, Alain, Hébert, Terence E., Chatenet, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424217/
https://www.ncbi.nlm.nih.gov/pubmed/34389356
http://dx.doi.org/10.1016/j.jbc.2021.101057

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