Frame-shifted APOBEC3A encodes two alternative proapoptotic proteins that target the mitochondrial network

The human APOBEC3A (A3A) cytidine deaminase is a powerful DNA mutator enzyme recognized as a major source of somatic mutations in tumor cell genomes. However, there is a discrepancy between APOBEC3A mRNA levels after interferon stimulation in myeloid cells and A3A detection at the protein level. To...

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Detalles Bibliográficos
Autores principales: Caval, Vincent, Suspène, Rodolphe, Khalfi, Pierre, Gaillard, Julien, Caignard, Grégory, Vitour, Damien, Roingeard, Philippe, Vartanian, Jean-Pierre, Wain-Hobson, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424220/
https://www.ncbi.nlm.nih.gov/pubmed/34403699
http://dx.doi.org/10.1016/j.jbc.2021.101081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424220/
https://www.ncbi.nlm.nih.gov/pubmed/34403699
http://dx.doi.org/10.1016/j.jbc.2021.101081

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