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Frame-shifted APOBEC3A encodes two alternative proapoptotic proteins that target the mitochondrial network

The human APOBEC3A (A3A) cytidine deaminase is a powerful DNA mutator enzyme recognized as a major source of somatic mutations in tumor cell genomes. However, there is a discrepancy between APOBEC3A mRNA levels after interferon stimulation in myeloid cells and A3A detection at the protein level. To...

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Detalles Bibliográficos
Autores principales:	Caval, Vincent, Suspène, Rodolphe, Khalfi, Pierre, Gaillard, Julien, Caignard, Grégory, Vitour, Damien, Roingeard, Philippe, Vartanian, Jean-Pierre, Wain-Hobson, Simon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424220/ https://www.ncbi.nlm.nih.gov/pubmed/34403699 http://dx.doi.org/10.1016/j.jbc.2021.101081

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