Integrated multiomics analysis identifies molecular landscape perturbations during hyperammonemia in skeletal muscle and myotubes

Ammonia is a cytotoxic molecule generated during normal cellular functions. Dysregulated ammonia metabolism, which is evident in many chronic diseases such as liver cirrhosis, heart failure, and chronic obstructive pulmonary disease, initiates a hyperammonemic stress response in tissues including sk...

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Detalles Bibliográficos
Autores principales: Welch, Nicole, Singh, Shashi Shekhar, Kumar, Avinash, Dhruba, Saugato Rahman, Mishra, Saurabh, Sekar, Jinendiran, Bellar, Annette, Attaway, Amy H., Chelluboyina, Aruna, Willard, Belinda B., Li, Ling, Huo, Zhiguang, Karnik, Sadashiva S., Esser, Karyn, Longworth, Michelle S., Shah, Yatrik M., Davuluri, Gangarao, Pal, Ranadip, Dasarathy, Srinivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424232/
https://www.ncbi.nlm.nih.gov/pubmed/34343564
http://dx.doi.org/10.1016/j.jbc.2021.101023

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