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Identification of novel microtubule inhibitors effective in fission yeast and human cells and their effects on breast cancer cell lines

Microtubules are critical for a variety of cellular processes such as chromosome segregation, intracellular transport and cell shape. Drugs against microtubules have been widely used in cancer chemotherapies, though the acquisition of drug resistance has been a significant issue for their use. To id...

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Detalles Bibliográficos
Autores principales: Morishita, Jun, Nurse, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424300/
https://www.ncbi.nlm.nih.gov/pubmed/34493069
http://dx.doi.org/10.1098/rsob.210161

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