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Identification of novel microtubule inhibitors effective in fission yeast and human cells and their effects on breast cancer cell lines
Microtubules are critical for a variety of cellular processes such as chromosome segregation, intracellular transport and cell shape. Drugs against microtubules have been widely used in cancer chemotherapies, though the acquisition of drug resistance has been a significant issue for their use. To id...
Autores principales: | Morishita, Jun, Nurse, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424300/ https://www.ncbi.nlm.nih.gov/pubmed/34493069 http://dx.doi.org/10.1098/rsob.210161 |
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