Cargando…
Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation
MicroRNAs (miRNA) are prerequisite for cardiovascular functions. miRNA miR-208 b is a cardio-specific miRNA with tissue (atrial) levels elevated in atrial fibrillation (AFib) and blood levels significantly elevated in myocardial infarction. We calculated serum levels of miR-208 b in paroxysmal and p...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424364/ https://www.ncbi.nlm.nih.gov/pubmed/34474768 http://dx.doi.org/10.1016/j.ihj.2021.06.018 |
_version_ | 1783749659901034496 |
---|---|
author | Paul, Abraham Pai, Praveen G. Ariyannur, Prasanth S. Joy, Reenu Anne |
author_facet | Paul, Abraham Pai, Praveen G. Ariyannur, Prasanth S. Joy, Reenu Anne |
author_sort | Paul, Abraham |
collection | PubMed |
description | MicroRNAs (miRNA) are prerequisite for cardiovascular functions. miRNA miR-208 b is a cardio-specific miRNA with tissue (atrial) levels elevated in atrial fibrillation (AFib) and blood levels significantly elevated in myocardial infarction. We calculated serum levels of miR-208 b in paroxysmal and persistent AFib, embolic cerebrovascular accident patients with AFib as possible etiology and controls. There was a statistically significant change of miR-208 b levels in paroxysmal (p = 0.044) and persistent (p = 0.040) AFib patients, but not for embolic CVA patients. miR-208 b could serve as a new serum marker for paroxysmal AFib. |
format | Online Article Text |
id | pubmed-8424364 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-84243642021-09-13 Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation Paul, Abraham Pai, Praveen G. Ariyannur, Prasanth S. Joy, Reenu Anne Indian Heart J Research Brief MicroRNAs (miRNA) are prerequisite for cardiovascular functions. miRNA miR-208 b is a cardio-specific miRNA with tissue (atrial) levels elevated in atrial fibrillation (AFib) and blood levels significantly elevated in myocardial infarction. We calculated serum levels of miR-208 b in paroxysmal and persistent AFib, embolic cerebrovascular accident patients with AFib as possible etiology and controls. There was a statistically significant change of miR-208 b levels in paroxysmal (p = 0.044) and persistent (p = 0.040) AFib patients, but not for embolic CVA patients. miR-208 b could serve as a new serum marker for paroxysmal AFib. Elsevier 2021 2021-07-01 /pmc/articles/PMC8424364/ /pubmed/34474768 http://dx.doi.org/10.1016/j.ihj.2021.06.018 Text en © 2021 Cardiological Society of India. Published by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Brief Paul, Abraham Pai, Praveen G. Ariyannur, Prasanth S. Joy, Reenu Anne Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation |
title | Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation |
title_full | Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation |
title_fullStr | Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation |
title_full_unstemmed | Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation |
title_short | Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation |
title_sort | diagnostic accuracy of microrna 208b level with respect to different types of atrial fibrillation |
topic | Research Brief |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424364/ https://www.ncbi.nlm.nih.gov/pubmed/34474768 http://dx.doi.org/10.1016/j.ihj.2021.06.018 |
work_keys_str_mv | AT paulabraham diagnosticaccuracyofmicrorna208blevelwithrespecttodifferenttypesofatrialfibrillation AT paipraveeng diagnosticaccuracyofmicrorna208blevelwithrespecttodifferenttypesofatrialfibrillation AT ariyannurprasanths diagnosticaccuracyofmicrorna208blevelwithrespecttodifferenttypesofatrialfibrillation AT joyreenuanne diagnosticaccuracyofmicrorna208blevelwithrespecttodifferenttypesofatrialfibrillation |