Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation

MicroRNAs (miRNA) are prerequisite for cardiovascular functions. miRNA miR-208 b is a cardio-specific miRNA with tissue (atrial) levels elevated in atrial fibrillation (AFib) and blood levels significantly elevated in myocardial infarction. We calculated serum levels of miR-208 b in paroxysmal and p...

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Autores principales: Paul, Abraham, Pai, Praveen G., Ariyannur, Prasanth S., Joy, Reenu Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424364/
https://www.ncbi.nlm.nih.gov/pubmed/34474768
http://dx.doi.org/10.1016/j.ihj.2021.06.018
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author Paul, Abraham
Pai, Praveen G.
Ariyannur, Prasanth S.
Joy, Reenu Anne
author_facet Paul, Abraham
Pai, Praveen G.
Ariyannur, Prasanth S.
Joy, Reenu Anne
author_sort Paul, Abraham
collection PubMed
description MicroRNAs (miRNA) are prerequisite for cardiovascular functions. miRNA miR-208 b is a cardio-specific miRNA with tissue (atrial) levels elevated in atrial fibrillation (AFib) and blood levels significantly elevated in myocardial infarction. We calculated serum levels of miR-208 b in paroxysmal and persistent AFib, embolic cerebrovascular accident patients with AFib as possible etiology and controls. There was a statistically significant change of miR-208 b levels in paroxysmal (p = 0.044) and persistent (p = 0.040) AFib patients, but not for embolic CVA patients. miR-208 b could serve as a new serum marker for paroxysmal AFib.
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spelling pubmed-84243642021-09-13 Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation Paul, Abraham Pai, Praveen G. Ariyannur, Prasanth S. Joy, Reenu Anne Indian Heart J Research Brief MicroRNAs (miRNA) are prerequisite for cardiovascular functions. miRNA miR-208 b is a cardio-specific miRNA with tissue (atrial) levels elevated in atrial fibrillation (AFib) and blood levels significantly elevated in myocardial infarction. We calculated serum levels of miR-208 b in paroxysmal and persistent AFib, embolic cerebrovascular accident patients with AFib as possible etiology and controls. There was a statistically significant change of miR-208 b levels in paroxysmal (p = 0.044) and persistent (p = 0.040) AFib patients, but not for embolic CVA patients. miR-208 b could serve as a new serum marker for paroxysmal AFib. Elsevier 2021 2021-07-01 /pmc/articles/PMC8424364/ /pubmed/34474768 http://dx.doi.org/10.1016/j.ihj.2021.06.018 Text en © 2021 Cardiological Society of India. Published by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Brief
Paul, Abraham
Pai, Praveen G.
Ariyannur, Prasanth S.
Joy, Reenu Anne
Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation
title Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation
title_full Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation
title_fullStr Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation
title_full_unstemmed Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation
title_short Diagnostic accuracy of MicroRNA 208b level with respect to different types of atrial fibrillation
title_sort diagnostic accuracy of microrna 208b level with respect to different types of atrial fibrillation
topic Research Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424364/
https://www.ncbi.nlm.nih.gov/pubmed/34474768
http://dx.doi.org/10.1016/j.ihj.2021.06.018
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