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Magnesium implantation or supplementation ameliorates bone disorder in CFTR-mutant mice through an ATF4-dependent Wnt/β-catenin signaling

Magnesium metal and its alloys are being developed as effective orthopedic implants; however, the mechanisms underlying the actions of magnesium on bones remain unclear. Cystic fibrosis, the most common genetic disease in Caucasians caused by the mutation of CFTR, has shown bone disorder as a key cl...

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Detalles Bibliográficos
Autores principales: Xu, Jiankun, Hu, Peijie, Zhang, Xiaotian, Chen, Junjiang, Wang, Jiali, Zhang, Jieting, Chen, Ziyi, Yu, Mei Kuen, Chung, Yiu Wa, Wang, Yan, Zhang, Xiaohu, Zhang, Yifeng, Zheng, Nianye, Yao, Hao, Yue, Jiang, Chan, Hsiao Chang, Qin, Ling, Ruan, Ye Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424424/
https://www.ncbi.nlm.nih.gov/pubmed/34541389
http://dx.doi.org/10.1016/j.bioactmat.2021.06.034