Chronic White Matter Inflammation and Serum Neurofilament Levels in Multiple Sclerosis

OBJECTIVE: To assess whether chronic white matter inflammation in patients with multiple sclerosis (MS) as detected in vivo by paramagnetic rim MRI lesions (PRLs) is associated with higher serum neurofilament light chain (sNfL) levels, a marker of neuroaxonal damage. METHODS: In 118 patients with MS...

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Detalles Bibliográficos
Autores principales: Maggi, Pietro, Kuhle, Jens, Schädelin, Sabine, van der Meer, Franziska, Weigel, Matthias, Galbusera, Riccardo, Mathias, Amandine, Lu, Po-Jui, Rahmanzadeh, Reza, Benkert, Pascal, La Rosa, Francesco, Bach Cuadra, Meritxell, Sati, Pascal, Théaudin, Marie, Pot, Caroline, van Pesch, Vincent, Leppert, David, Stadelmann, Christine, Kappos, Ludwig, Du Pasquier, Renaud, Reich, Daniel S., Absinta, Martina, Granziera, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424501/
https://www.ncbi.nlm.nih.gov/pubmed/34088875
http://dx.doi.org/10.1212/WNL.0000000000012326

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