Integrated protocol for exitron and exitron-derived neoantigen identification using human RNA-seq data with ScanExitron and ScanNeo

Exitron splicing (EIS) events in cancers can disrupt functional protein domains to cause cancer driver effects. EIS has been recognized as a new source of tumor neoantigens. Here, we describe an integrated protocol for EIS and EIS-derived neoantigen identification using RNA-seq data. The protocol co...

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Detalles Bibliográficos
Autores principales: Wang, Ting-You, Yang, Rendong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424586/
https://www.ncbi.nlm.nih.gov/pubmed/34522901
http://dx.doi.org/10.1016/j.xpro.2021.100788
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author Wang, Ting-You
Yang, Rendong
author_facet Wang, Ting-You
Yang, Rendong
author_sort Wang, Ting-You
collection PubMed
description Exitron splicing (EIS) events in cancers can disrupt functional protein domains to cause cancer driver effects. EIS has been recognized as a new source of tumor neoantigens. Here, we describe an integrated protocol for EIS and EIS-derived neoantigen identification using RNA-seq data. The protocol constitutes a step-by-step guide from data collection to neoantigen prediction. For complete details on the use and execution of this protocol, please refer to Wang et al. (2021).
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spelling pubmed-84245862021-09-13 Integrated protocol for exitron and exitron-derived neoantigen identification using human RNA-seq data with ScanExitron and ScanNeo Wang, Ting-You Yang, Rendong STAR Protoc Protocol Exitron splicing (EIS) events in cancers can disrupt functional protein domains to cause cancer driver effects. EIS has been recognized as a new source of tumor neoantigens. Here, we describe an integrated protocol for EIS and EIS-derived neoantigen identification using RNA-seq data. The protocol constitutes a step-by-step guide from data collection to neoantigen prediction. For complete details on the use and execution of this protocol, please refer to Wang et al. (2021). Elsevier 2021-09-03 /pmc/articles/PMC8424586/ /pubmed/34522901 http://dx.doi.org/10.1016/j.xpro.2021.100788 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Protocol
Wang, Ting-You
Yang, Rendong
Integrated protocol for exitron and exitron-derived neoantigen identification using human RNA-seq data with ScanExitron and ScanNeo
title Integrated protocol for exitron and exitron-derived neoantigen identification using human RNA-seq data with ScanExitron and ScanNeo
title_full Integrated protocol for exitron and exitron-derived neoantigen identification using human RNA-seq data with ScanExitron and ScanNeo
title_fullStr Integrated protocol for exitron and exitron-derived neoantigen identification using human RNA-seq data with ScanExitron and ScanNeo
title_full_unstemmed Integrated protocol for exitron and exitron-derived neoantigen identification using human RNA-seq data with ScanExitron and ScanNeo
title_short Integrated protocol for exitron and exitron-derived neoantigen identification using human RNA-seq data with ScanExitron and ScanNeo
title_sort integrated protocol for exitron and exitron-derived neoantigen identification using human rna-seq data with scanexitron and scanneo
topic Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424586/
https://www.ncbi.nlm.nih.gov/pubmed/34522901
http://dx.doi.org/10.1016/j.xpro.2021.100788
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