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Scutellarin-induced A549 cell apoptosis depends on activation of the transforming growth factor-β1/smad2/ROS/caspase-3 pathway

Scutellarin plays an anti-tumor role in A549 lung cancer cells, but the underlying mechanism is unclear. In this study, scutellarin was used to treat A549 cells for 12, 24, and 48 h, followed by the addition of Tempo, a selective scavenger of mitochondrial reactive oxygen species (ROS) and SB431542,...

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Detalles Bibliográficos
Autores principales:	Zhang, Guang-Yan, Chen, Wei-Yong, Li, Xiao-Bo, Ke, Hua, Zhou, Xue-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	De Gruyter 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424968/ https://www.ncbi.nlm.nih.gov/pubmed/34568577 http://dx.doi.org/10.1515/biol-2021-0085

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