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Bufalin suppresses tumour microenvironment-mediated angiogenesis by inhibiting the STAT3 signalling pathway

BACKGROUND: Antiangiogenic therapy has increasingly become an important strategy for the treatment of colorectal cancer. Recent studies have shown that the tumour microenvironment (TME) promotes tumour angiogenesis. Bufalin is an active antitumour compound whose efficacy has been indicated by previo...

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Detalles Bibliográficos
Autores principales: Fang, Kai, Zhan, Yueping, Zhu, Ruiqiu, Wang, Yuqian, Wu, Chengqi, Sun, Min, Qiu, Yanyan, Yuan, Zeting, Liang, Xin, Yin, Peihao, Xu, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424978/
https://www.ncbi.nlm.nih.gov/pubmed/34496870
http://dx.doi.org/10.1186/s12967-021-03058-z