An ADAR1-dependent RNA editing event in the cyclin-dependent kinase CDK13 promotes thyroid cancer hallmarks

BACKGROUND: Adenosine deaminases acting on RNA (ADARs) modify many cellular RNAs by catalyzing the conversion of adenosine to inosine (A-to-I), and their deregulation is associated with several cancers. We recently showed that A-to-I editing is elevated in thyroid tumors and that ADAR1 is functional...

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Detalles Bibliográficos
Autores principales: Ramírez-Moya, Julia, Miliotis, Christos, Baker, Allison R., Gregory, Richard I., Slack, Frank J., Santisteban, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424981/
https://www.ncbi.nlm.nih.gov/pubmed/34496885
http://dx.doi.org/10.1186/s12943-021-01401-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424981/
https://www.ncbi.nlm.nih.gov/pubmed/34496885
http://dx.doi.org/10.1186/s12943-021-01401-y

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