Pulmonary delivery of the broad-spectrum matrix metalloproteinase inhibitor marimastat diminishes multiwalled carbon nanotube-induced circulating bioactivity without reducing pulmonary inflammation

BACKGROUND: Multiwalled carbon nanotubes (MWCNT) are an increasingly utilized engineered nanomaterial that pose the potential for significant risk of exposure-related health outcomes. The mechanism(s) underlying MWCNT-induced toxicity to extrapulmonary sites are still being defined. MWCNT-induced se...

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Detalles Bibliográficos
Autores principales: Young, Tamara L., Mostovenko, Ekaterina, Denson, Jesse L., Begay, Jessica G., Lucas, Selita N., Herbert, Guy, Zychowski, Katherine, Hunter, Russell, Salazar, Raul, Wang, Ting, Fraser, Kelly, Erdely, Aaron, Ottens, Andrew K., Campen, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8424988/
https://www.ncbi.nlm.nih.gov/pubmed/34496918
http://dx.doi.org/10.1186/s12989-021-00427-w

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