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Clinical efficacy of bone transport technology in Chinese older patients with infectious bone nonunion after open tibial fracture
OBJECTIVE: This study was designed for the first time to analyze clinical efficacy of bone transport technology in Chinese older patients with infectious bone nonunion after open tibial fracture. METHODS: This study retrospectively analyzed 220 older patients with infectious bone nonunion after open...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425085/ https://www.ncbi.nlm.nih.gov/pubmed/34493200 http://dx.doi.org/10.1186/s12877-021-02409-1 |
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author | Wen, Ying Liu, Peiming Wang, Zhichao Li, Ning |
author_facet | Wen, Ying Liu, Peiming Wang, Zhichao Li, Ning |
author_sort | Wen, Ying |
collection | PubMed |
description | OBJECTIVE: This study was designed for the first time to analyze clinical efficacy of bone transport technology in Chinese older patients with infectious bone nonunion after open tibial fracture. METHODS: This study retrospectively analyzed 220 older patients with infectious bone nonunion after open tibial fracture. There were 110 patients receiving bone transport technology (Group A) and 110 patients receiving membrane induction technique with antibiotic bone cement (Group B). RESULTS: There were 164 male patients and 56 female patients, with an age range of 65 to 71 years and an average age of 67 ± 1.3 years. Traffic accident, high-fall injury and crush injury account for 45.5, 27.7 and 26.8%, respectively. Age, gender, histories, causes and fracture location had no significant difference between the two groups (P > 0.05 for all). Operation time in the Group A was significantly shorter than that in the Group B (P < 0.05). Linear and positional alignment (70.9 vs. 57.3), American Knee Society knee function score (167.7 ± 14.9 vs. 123.8 ± 15.7), Baird-Jackson ankle function score (89.9 ± 3.5 vs. 78.4 ± 4.9), bone healing index (43.0 ± 2.0 vs. 44.3 ± 3.0) and clinical recovery (8.2 vs. 4.5) of patients in the Group A were significantly better than those in the Group B (P < 0.05 for all). Wound infection in the Group A (7.3%) was significantly less than that in the Group B (16.4%; P < 0.05). There were neither a neurovascular complication nor a recurrence of infection in the two groups. CONCLUSION: Bone transport technology achieved better knee and ankle joint function recovery and superior bone healing and clinical efficacy than membrane induction technique with antibiotic bone cement, suggesting that bone transport technique is worthy of extensive promotion to improve clinical condition of older patients with infectious bone nonunion after open tibial fracture. |
format | Online Article Text |
id | pubmed-8425085 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-84250852021-09-10 Clinical efficacy of bone transport technology in Chinese older patients with infectious bone nonunion after open tibial fracture Wen, Ying Liu, Peiming Wang, Zhichao Li, Ning BMC Geriatr Research OBJECTIVE: This study was designed for the first time to analyze clinical efficacy of bone transport technology in Chinese older patients with infectious bone nonunion after open tibial fracture. METHODS: This study retrospectively analyzed 220 older patients with infectious bone nonunion after open tibial fracture. There were 110 patients receiving bone transport technology (Group A) and 110 patients receiving membrane induction technique with antibiotic bone cement (Group B). RESULTS: There were 164 male patients and 56 female patients, with an age range of 65 to 71 years and an average age of 67 ± 1.3 years. Traffic accident, high-fall injury and crush injury account for 45.5, 27.7 and 26.8%, respectively. Age, gender, histories, causes and fracture location had no significant difference between the two groups (P > 0.05 for all). Operation time in the Group A was significantly shorter than that in the Group B (P < 0.05). Linear and positional alignment (70.9 vs. 57.3), American Knee Society knee function score (167.7 ± 14.9 vs. 123.8 ± 15.7), Baird-Jackson ankle function score (89.9 ± 3.5 vs. 78.4 ± 4.9), bone healing index (43.0 ± 2.0 vs. 44.3 ± 3.0) and clinical recovery (8.2 vs. 4.5) of patients in the Group A were significantly better than those in the Group B (P < 0.05 for all). Wound infection in the Group A (7.3%) was significantly less than that in the Group B (16.4%; P < 0.05). There were neither a neurovascular complication nor a recurrence of infection in the two groups. CONCLUSION: Bone transport technology achieved better knee and ankle joint function recovery and superior bone healing and clinical efficacy than membrane induction technique with antibiotic bone cement, suggesting that bone transport technique is worthy of extensive promotion to improve clinical condition of older patients with infectious bone nonunion after open tibial fracture. BioMed Central 2021-09-07 /pmc/articles/PMC8425085/ /pubmed/34493200 http://dx.doi.org/10.1186/s12877-021-02409-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Wen, Ying Liu, Peiming Wang, Zhichao Li, Ning Clinical efficacy of bone transport technology in Chinese older patients with infectious bone nonunion after open tibial fracture |
title | Clinical efficacy of bone transport technology in Chinese older patients with infectious bone nonunion after open tibial fracture |
title_full | Clinical efficacy of bone transport technology in Chinese older patients with infectious bone nonunion after open tibial fracture |
title_fullStr | Clinical efficacy of bone transport technology in Chinese older patients with infectious bone nonunion after open tibial fracture |
title_full_unstemmed | Clinical efficacy of bone transport technology in Chinese older patients with infectious bone nonunion after open tibial fracture |
title_short | Clinical efficacy of bone transport technology in Chinese older patients with infectious bone nonunion after open tibial fracture |
title_sort | clinical efficacy of bone transport technology in chinese older patients with infectious bone nonunion after open tibial fracture |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425085/ https://www.ncbi.nlm.nih.gov/pubmed/34493200 http://dx.doi.org/10.1186/s12877-021-02409-1 |
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