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Gut microbiota regulation of P-glycoprotein in the intestinal epithelium in maintenance of homeostasis

BACKGROUND: P-glycoprotein (P-gp) plays a critical role in protection of the intestinal epithelia by mediating efflux of drugs/xenobiotics from the intestinal mucosa into the gut lumen. Recent studies bring to light that P-gp also confers a critical link in communication between intestinal mucosal b...

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Detalles Bibliográficos
Autores principales: Foley, Sage E., Tuohy, Christine, Dunford, Merran, Grey, Michael J., De Luca, Heidi, Cawley, Caitlin, Szabady, Rose L., Maldonado-Contreras, Ana, Houghton, Jean Marie, Ward, Doyle V., Mrsny, Randall J., McCormick, Beth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425172/
https://www.ncbi.nlm.nih.gov/pubmed/34493329
http://dx.doi.org/10.1186/s40168-021-01137-3