Cargando…

Pan-cancer Analysis of NEDD4L and Its Tumor Suppressor Effects in Clear Cell Renal Cell Carcinoma

The expression level of NEDD4L, an E3 ubiquitin ligase, has changed significantly in human cancers. In this study, we aimed to study the expression of NEDD4L in pan-carcinoma and its function in malignant tumors. We analyzed the gene expression level of NEDD4L in pan-cancer from The Cancer Genome At...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dong, Huiyue, Zhu, Ling, Sun, Jingjing, Zhang, Yi, Cui, Qiang, Wu, Lin, Chen, Shushang, Lu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425189/ https://www.ncbi.nlm.nih.gov/pubmed/34539897 http://dx.doi.org/10.7150/jca.58004

Ejemplares similares

ABAT and ALDH6A1, regulated by transcription factor HNF4A, suppress tumorigenic capability in clear cell renal cell carcinoma
por: Lu, Jun, et al.
Publicado: (2020)

Integrated bioinformatics analysis of the NEDD4 family reveals a prognostic value of NEDD4L in clear-cell renal cell cancer
por: Zhao, Hui, et al.
Publicado: (2021)

Classification of Clear Cell Renal Cell Carcinoma based on Tumor Suppressor Genomic Profiling
por: Zhong, Weimin, et al.
Publicado: (2021)

KDF1, a Novel Tumor Suppressor in Clear Cell Renal Cell Carcinoma
por: Zheng, Jing-min, et al.
Publicado: (2021)

RNF43 is a novel tumor-suppressor and prognostic indicator in clear cell renal cell carcinoma
por: ZHU, DAWEI, et al.
Publicado: (2022)

Overexpression of NEDD9 in renal cell carcinoma is associated with tumor migration and invasion
por: Wang, Jue, et al.
Publicado: (2017)

Follistatin-like protein 1 plays a tumor suppressor role in clear-cell renal cell carcinoma
por: Liu, Yan, et al.
Publicado: (2018)

Hypermethylation of the 16q23.1 Tumor Suppressor Gene ADAMTS18 in Clear Cell Renal Cell Carcinoma
por: Xu, Ben, et al.
Publicado: (2015)

Promoter methylation inhibits expression of tumor suppressor KIBRA in human clear cell renal cell carcinoma
por: Schelleckes, Katrin, et al.
Publicado: (2017)

RhoB Acts as a Tumor Suppressor That Inhibits Malignancy of Clear Cell Renal Cell Carcinoma
por: Chen, Weihao, et al.
Publicado: (2016)

Tumor Suppressor Properties of Small C-Terminal Domain Phosphatases in Clear Cell Renal Cell Carcinoma
por: Krasnov, George S., et al.
Publicado: (2023)

SH3BGRL2, a new downregulated tumor suppressor in clear cell renal cell carcinomas
por: Dufies, Maeva
Publicado: (2020)

Frequent Epigenetic Suppression of Tumor Suppressor Gene Glutathione Peroxidase 3 by Promoter Hypermethylation and Its Clinical Implication in Clear Cell Renal Cell Carcinoma
por: Liu, Qianling, et al.
Publicado: (2015)

Transmembrane Transporter Sema3D Serves as a Tumor Suppressor in Localized Clear Cell Renal Cell Carcinoma
por: Xie, Ruiyang, et al.
Publicado: (2022)

The RNA-binding protein KSRP aggravates malignant progression of clear cell renal cell carcinoma through transcriptional inhibition and post-transcriptional destabilization of the NEDD4L ubiquitin ligase
por: Yang, Yi-Chieh, et al.
Publicado: (2023)

Decreased expression of RASSF1A tumor suppressor gene is associated with worse prognosis in clear cell renal cell carcinoma
por: KLACZ, JAKUB, et al.
Publicado: (2015)

Two Single Nucleotide Polymorphisms in the Von Hippel-Lindau Tumor Suppressor Gene in Patients with Clear Cell Renal Cell Carcinoma
por: Chrabańska, Magdalena, et al.
Publicado: (2023)

CMTM4 is frequently downregulated and functions as a tumour suppressor in clear cell renal cell carcinoma
por: Li, Ting, et al.
Publicado: (2015)

The Tumor Immune Microenvironment in Clear Cell Renal Cell Carcinoma
por: Monjaras-Avila, Cesar U., et al.
Publicado: (2023)

Pan-Cancer Transcriptomic Analysis Identifies PLK1 Crucial for the Tumorigenesis of Clear Cell Renal Cell Carcinoma
por: Qian, Yiguan, et al.
Publicado: (2022)

Functional Studies on Primary Tubular Epithelial Cells Indicate a Tumor Suppressor Role of SETD2 in Clear Cell Renal Cell Carcinoma()
por: Li, Jun, et al.
Publicado: (2016)

miR-106b-5p targets tumor suppressor gene SETD2 to inactive its function in clear cell renal cell carcinoma
por: Xiang, Wei, et al.
Publicado: (2015)

TLN2 functions as a tumor suppressor in clear cell renal cell carcinoma via inactivation of the Wnt/β-catenin signaling pathway
por: Cai, Jingshuang, et al.
Publicado: (2022)

TRPV1 acts as a Tumor Suppressor and is associated with Immune Cell Infiltration in Clear Cell Renal Cell Carcinoma: evidence from integrated analysis
por: Zheng, Long, et al.
Publicado: (2020)

NEDD9 promotes cancer stemness by recruiting myeloid-derived suppressor cells via CXCL8 in esophageal squamous cell carcinoma
por: Yue, Dongli, et al.
Publicado: (2021)

Tumor-to-tumor metastases: papillary thyroid carcinoma into a clear cell renal cell carcinoma
por: Song, Jin Soo Andy, et al.
Publicado: (2017)

siRNA Suppression of NEDD9 Inhibits Proliferation and Enhances Apoptosis in Renal Cell Carcinoma
por: Wang, Jue, et al.
Publicado: (2015)

Molecular subtyping and characterization of clear cell renal cell carcinoma by tumor differentiation trajectories
por: Pan, Xiu-wu, et al.
Publicado: (2023)

The putative tumor suppressor, miR-199a, regulated by Snail, modulates clear cell renal cell carcinoma aggressiveness by repressing ROCK1
por: Zhang, Xiao, et al.
Publicado: (2017)

Pan-cancer analysis of cuproptosis regulation patterns and identification of mTOR-target responder in clear cell renal cell carcinoma
por: Long, Shichao, et al.
Publicado: (2022)

Metabolic Understanding of the Genetic Dysregulation in the Tumor Microenvironment of Kidney Renal Clear Cell Carcinoma
por: Xie, Junwei, et al.
Publicado: (2022)

Prognostic significance and tumor-immune infiltration of mTOR in clear cell renal cell carcinoma
por: Li, Na, et al.
Publicado: (2021)

Identification of the Prognostic Value Among Suppressor Of Cytokine Signaling Family Members in Kidney Renal Clear Cell Carcinoma
por: Li, Changjiu, et al.
Publicado: (2021)

Tumor-derived exosomes facilitate tumor cells escape from drug therapy in clear cell renal cell carcinoma
por: Wang, Xiaogang, et al.
Publicado: (2020)

Multi-omics pan-cancer study of cuproptosis core gene FDX1 and its role in kidney renal clear cell carcinoma
por: Xu, Jiahao, et al.
Publicado: (2022)

Glycogen metabolism is dispensable for tumor progression in clear cell renal cell carcinoma
por: Xie, Hong, et al.
Publicado: (2021)

Tumor heterogeneity in VHL drives metastasis in clear cell renal cell carcinoma
por: Hu, Junhui, et al.
Publicado: (2023)

Pan‐cancer analysis revealing DAAM1 as a novel predictive biomarker for PD‐1/PD‐L1 blockade in clear cell renal cell carcinoma
por: Mei, Jie, et al.
Publicado: (2022)

Prognostic Inflammasome-Related Signature Construction in Kidney Renal Clear Cell Carcinoma Based on a Pan-Cancer Landscape
por: Zheng, Tianyu, et al.
Publicado: (2020)

Systematic pan-cancer analysis identifies gasdermin B as an immunological and prognostic biomarker for kidney renal clear cell carcinoma
por: Liu, Xuehe, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_s0fodoh6citk01me3jri08uk3n