Follicular and serum levels of vitamin D in women with unexplained infertility and their relationship with in vitro fertilization outcome: an observational pilot study

INTRODUCTION: Follicular and serum vitamin D are considered potential markers of the oocyte and embryos’ quality and predictors of in vitro fertilization (IVF) outcomes. METHODS: This retrospective cross-sectional study correlated vitamin D in sera and follicular fluid of women with unexplained infe...

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Detalles Bibliográficos
Autores principales: Jeremic, Ana, Mikovic, Zeljko, Soldatovic, Ivan, Sudar-Milovanovic, Emina, Isenovic, Esma R., Perovic, Milan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425239/
https://www.ncbi.nlm.nih.gov/pubmed/34522272
http://dx.doi.org/10.5114/aoms/141185
Descripción
Sumario:INTRODUCTION: Follicular and serum vitamin D are considered potential markers of the oocyte and embryos’ quality and predictors of in vitro fertilization (IVF) outcomes. METHODS: This retrospective cross-sectional study correlated vitamin D in sera and follicular fluid of women with unexplained infertility mutually and with IVF outcomes. ELISA was used for measuring vitamin D. RESULTS: The results show positive correlation only between follicular and serum levels of vitamin D (Rho = 0.615, p = 0.025), and between follicular levels of vitamin D and the percentage of embryo fragmentation (Rho = 0.544; p = 0.036). CONCLUSIONS: The results suggest that serum and follicular fluid vitamin D measurements could be complementary tools to the routine assessment of embryos.

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