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Preterm birth, unplanned hospital contact, and mortality in infants born to teenage mothers in five countries: An administrative data cohort study

BACKGROUND: Young maternal age is associated with lower birthweight and higher rates of preterm birth and childhood hospitalisations. Internationally, teen pregnancy rates vary widely, reflecting differences in social, welfare, and health care factors in different cultural contexts. OBJECTIVES: To d...

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Autores principales: Harron, Katie, Verfuerden, Maximiliane, Ibiebele, Ibinabo, Liu, Can, Kopp, Alex, Guttmann, Astrid, Ford, Jane, van der Meulen, Jan, Hjern, Anders, Gilbert, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425326/
https://www.ncbi.nlm.nih.gov/pubmed/32343005
http://dx.doi.org/10.1111/ppe.12685
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author Harron, Katie
Verfuerden, Maximiliane
Ibiebele, Ibinabo
Liu, Can
Kopp, Alex
Guttmann, Astrid
Ford, Jane
van der Meulen, Jan
Hjern, Anders
Gilbert, Ruth
author_facet Harron, Katie
Verfuerden, Maximiliane
Ibiebele, Ibinabo
Liu, Can
Kopp, Alex
Guttmann, Astrid
Ford, Jane
van der Meulen, Jan
Hjern, Anders
Gilbert, Ruth
author_sort Harron, Katie
collection PubMed
description BACKGROUND: Young maternal age is associated with lower birthweight and higher rates of preterm birth and childhood hospitalisations. Internationally, teen pregnancy rates vary widely, reflecting differences in social, welfare, and health care factors in different cultural contexts. OBJECTIVES: To determine whether the increased risk of adverse infant outcomes among teenage mothers varies by country, reflecting different national teenage birth rates and country‐specific social/welfare policies, in Scotland (higher teenage pregnancy rates), England, New South Wales (NSW; Australia), Ontario (Canada), and Sweden (lower rates). METHODS: We used administrative hospital data capturing 3 002 749 singleton births surviving to postnatal discharge between 2010 and 2014 (2008‐2012 for Sweden). We compared preterm birth (24‐36 weeks’ gestation), mortality within 12 months of postnatal discharge, unplanned hospital admissions, and emergency department visits within 12 months of postnatal discharge, for infants born to mothers aged 15‐19, 20‐24, 25‐29, and 30‐34 years. RESULTS: Compared to births to women aged 30‐34 years, risks of adverse outcomes among teenage mothers were higher in all countries, but the magnitude of effects was not related to country‐specific rates of teenage births. Teenage mothers had between 1.2% (95% confidence interval [CI] 0.7, 1.7, Sweden) and 2.0% (95% CI 1.4, 2.5, NSW) more preterm births, and between 9.8 (95% CI 7.2, 12.4, England) and 19.7 (95% CI 8.7, 30.6, Scotland) more deaths per 10 000 infants, compared with mothers aged 30‐34. Between 6.4% (95% CI 5.5, 7.4, NSW) and 25.4% (95% CI 24.7, 26.1, Ontario), more infants born to teenage mothers had unplanned hospital contacts compared with those born to mothers aged 30‐34. CONCLUSIONS: Regardless of country, infants born to teenage mothers had universally worse outcomes than those born to older mothers. This excess risk did not vary by national rates of livebirths to teenage mothers. Current mechanisms to support teenage mothers have not eliminated maternal age‐related disparities in infant outcomes; further strategies to mitigate excess risk in all countries are needed.
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spelling pubmed-84253262021-09-13 Preterm birth, unplanned hospital contact, and mortality in infants born to teenage mothers in five countries: An administrative data cohort study Harron, Katie Verfuerden, Maximiliane Ibiebele, Ibinabo Liu, Can Kopp, Alex Guttmann, Astrid Ford, Jane van der Meulen, Jan Hjern, Anders Gilbert, Ruth Paediatr Perinat Epidemiol Maternal Age Effects BACKGROUND: Young maternal age is associated with lower birthweight and higher rates of preterm birth and childhood hospitalisations. Internationally, teen pregnancy rates vary widely, reflecting differences in social, welfare, and health care factors in different cultural contexts. OBJECTIVES: To determine whether the increased risk of adverse infant outcomes among teenage mothers varies by country, reflecting different national teenage birth rates and country‐specific social/welfare policies, in Scotland (higher teenage pregnancy rates), England, New South Wales (NSW; Australia), Ontario (Canada), and Sweden (lower rates). METHODS: We used administrative hospital data capturing 3 002 749 singleton births surviving to postnatal discharge between 2010 and 2014 (2008‐2012 for Sweden). We compared preterm birth (24‐36 weeks’ gestation), mortality within 12 months of postnatal discharge, unplanned hospital admissions, and emergency department visits within 12 months of postnatal discharge, for infants born to mothers aged 15‐19, 20‐24, 25‐29, and 30‐34 years. RESULTS: Compared to births to women aged 30‐34 years, risks of adverse outcomes among teenage mothers were higher in all countries, but the magnitude of effects was not related to country‐specific rates of teenage births. Teenage mothers had between 1.2% (95% confidence interval [CI] 0.7, 1.7, Sweden) and 2.0% (95% CI 1.4, 2.5, NSW) more preterm births, and between 9.8 (95% CI 7.2, 12.4, England) and 19.7 (95% CI 8.7, 30.6, Scotland) more deaths per 10 000 infants, compared with mothers aged 30‐34. Between 6.4% (95% CI 5.5, 7.4, NSW) and 25.4% (95% CI 24.7, 26.1, Ontario), more infants born to teenage mothers had unplanned hospital contacts compared with those born to mothers aged 30‐34. CONCLUSIONS: Regardless of country, infants born to teenage mothers had universally worse outcomes than those born to older mothers. This excess risk did not vary by national rates of livebirths to teenage mothers. Current mechanisms to support teenage mothers have not eliminated maternal age‐related disparities in infant outcomes; further strategies to mitigate excess risk in all countries are needed. John Wiley and Sons Inc. 2020-04-28 2020-11 /pmc/articles/PMC8425326/ /pubmed/32343005 http://dx.doi.org/10.1111/ppe.12685 Text en © 2020 Authors. Paediatric and Perinatal Epidemiology published by John Wiley & Sons Ltd https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Maternal Age Effects
Harron, Katie
Verfuerden, Maximiliane
Ibiebele, Ibinabo
Liu, Can
Kopp, Alex
Guttmann, Astrid
Ford, Jane
van der Meulen, Jan
Hjern, Anders
Gilbert, Ruth
Preterm birth, unplanned hospital contact, and mortality in infants born to teenage mothers in five countries: An administrative data cohort study
title Preterm birth, unplanned hospital contact, and mortality in infants born to teenage mothers in five countries: An administrative data cohort study
title_full Preterm birth, unplanned hospital contact, and mortality in infants born to teenage mothers in five countries: An administrative data cohort study
title_fullStr Preterm birth, unplanned hospital contact, and mortality in infants born to teenage mothers in five countries: An administrative data cohort study
title_full_unstemmed Preterm birth, unplanned hospital contact, and mortality in infants born to teenage mothers in five countries: An administrative data cohort study
title_short Preterm birth, unplanned hospital contact, and mortality in infants born to teenage mothers in five countries: An administrative data cohort study
title_sort preterm birth, unplanned hospital contact, and mortality in infants born to teenage mothers in five countries: an administrative data cohort study
topic Maternal Age Effects
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425326/
https://www.ncbi.nlm.nih.gov/pubmed/32343005
http://dx.doi.org/10.1111/ppe.12685
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