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Stimulation of the Epithelial Na(+) Channel in Renal Principal Cells by Gs-Coupled Designer Receptors Exclusively Activated by Designer Drugs

The activity of the Epithelial Na(+) Channel (ENaC) in renal principal cells (PC) fine-tunes sodium excretion and consequently, affects blood pressure. The Gs-adenylyl cyclase-cAMP signal transduction pathway is believed to play a central role in the normal control of ENaC activity in PCs. The curre...

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Detalles Bibliográficos
Autores principales:	Soares, Antonio G., Contreras, Jorge, Archer, Crystal R., Mironova, Elena, Berdeaux, Rebecca, Stockand, James D., Abd El-Aziz, Tarek Mohamed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425396/ https://www.ncbi.nlm.nih.gov/pubmed/34512393 http://dx.doi.org/10.3389/fphys.2021.725782

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