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Comprehensive benchmarking of software for mapping whole genome bisulfite data: from read alignment to DNA methylation analysis

Whole genome bisulfite sequencing is currently at the forefront of epigenetic analysis, facilitating the nucleotide-level resolution of 5-methylcytosine (5mC) on a genome-wide scale. Specialized software have been developed to accommodate the unique difficulties in aligning such sequencing reads to...

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Detalles Bibliográficos
Autores principales: Nunn, Adam, Otto, Christian, Stadler, Peter F, Langenberger, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425420/
https://www.ncbi.nlm.nih.gov/pubmed/33624017
http://dx.doi.org/10.1093/bib/bbab021