Liver-specific deletion of mechanistic target of rapamycin does not protect against acetaminophen-induced liver injury in mice

BACKGROUND: Acetaminophen (APAP) overdose can cause liver injury and liver failure, which is one of the most common causes of drug-induced liver injury in the United States. Pharmacological activation of autophagy by inhibiting mechanistic target of rapamycin (mTOR) protects against APAP-induced liv...

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Detalles Bibliográficos
Autores principales: Sun, Hua, Ni, Hong-Min, McCracken, Jennifer M., Akakpo, Jephte Y, Fulte, Sam, McKeen, Tara, Jaeschke, Hartmut, Wang, Hua, Ding, Wen-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425470/
https://www.ncbi.nlm.nih.gov/pubmed/34504721
http://dx.doi.org/10.1016/j.livres.2021.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425470/
https://www.ncbi.nlm.nih.gov/pubmed/34504721
http://dx.doi.org/10.1016/j.livres.2021.03.001

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