Cargando…

HIV Infection Prevalence Significantly Intersects With COVID-19 Infection At the Area Level: A US County-Level Analysis

Limited empirical evidence exists about the extent to which the current HIV epidemic intersects with COVID-19 infections at the area/geographic level. Moreover, little is known about how demographic, social, economic, behavioral, and clinical determinants are jointly associated with these infectious...

Descripción completa

Detalles Bibliográficos
Autores principales: Luan, Hui, Song, Insang, Fiellin, David A., Ransome, Yusuf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425510/
https://www.ncbi.nlm.nih.gov/pubmed/34238821
http://dx.doi.org/10.1097/QAI.0000000000002758
_version_ 1783749860389814272
author Luan, Hui
Song, Insang
Fiellin, David A.
Ransome, Yusuf
author_facet Luan, Hui
Song, Insang
Fiellin, David A.
Ransome, Yusuf
author_sort Luan, Hui
collection PubMed
description Limited empirical evidence exists about the extent to which the current HIV epidemic intersects with COVID-19 infections at the area/geographic level. Moreover, little is known about how demographic, social, economic, behavioral, and clinical determinants are jointly associated with these infectious diseases. SETTING: Contiguous US counties (N = 3108). METHODS: We conducted a cross-sectional analysis and investigated the joint association between new HIV infection prevalence in 2018 and COVID-19 infections (January 22, 2020 and October 7, 2020) and explore the contribution of factors such as income inequality, binge drinking, and socioeconomic deprivation. We used Bayesian multivariate spatial models to estimate the cross-disease correlations between these diseases and identified hotspots, which we defined as a county with a posterior probability greater than 80% of being in the top decile of that disease. RESULTS: New HIV infection prevalence and COVID-19 infection moderately and significantly intersect [spatial correlation = 0.37, 95% credible interval (CrI) = 0.36–0.37]. Seventy-five counties, mostly in the south, were at elevated burden for HIV and COVID-19 infections. Higher income inequality was positively associated with both COVID-19 (relative risk 1.05, 95% CrI = 1.03–1.07) and HIV infection (relative risk = 1.12, 95% CrI = 1.09–1.15). CONCLUSIONS: We found that there is a considerable intersection between the current distribution of HIV burden with COVID-19 infections at the area level. We identified areas that federal funding and vaccination campaigns should prioritize for prevention and care efforts.
format Online
Article
Text
id pubmed-8425510
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher JAIDS Journal of Acquired Immune Deficiency Syndromes
record_format MEDLINE/PubMed
spelling pubmed-84255102021-09-09 HIV Infection Prevalence Significantly Intersects With COVID-19 Infection At the Area Level: A US County-Level Analysis Luan, Hui Song, Insang Fiellin, David A. Ransome, Yusuf J Acquir Immune Defic Syndr Epidemiology Limited empirical evidence exists about the extent to which the current HIV epidemic intersects with COVID-19 infections at the area/geographic level. Moreover, little is known about how demographic, social, economic, behavioral, and clinical determinants are jointly associated with these infectious diseases. SETTING: Contiguous US counties (N = 3108). METHODS: We conducted a cross-sectional analysis and investigated the joint association between new HIV infection prevalence in 2018 and COVID-19 infections (January 22, 2020 and October 7, 2020) and explore the contribution of factors such as income inequality, binge drinking, and socioeconomic deprivation. We used Bayesian multivariate spatial models to estimate the cross-disease correlations between these diseases and identified hotspots, which we defined as a county with a posterior probability greater than 80% of being in the top decile of that disease. RESULTS: New HIV infection prevalence and COVID-19 infection moderately and significantly intersect [spatial correlation = 0.37, 95% credible interval (CrI) = 0.36–0.37]. Seventy-five counties, mostly in the south, were at elevated burden for HIV and COVID-19 infections. Higher income inequality was positively associated with both COVID-19 (relative risk 1.05, 95% CrI = 1.03–1.07) and HIV infection (relative risk = 1.12, 95% CrI = 1.09–1.15). CONCLUSIONS: We found that there is a considerable intersection between the current distribution of HIV burden with COVID-19 infections at the area level. We identified areas that federal funding and vaccination campaigns should prioritize for prevention and care efforts. JAIDS Journal of Acquired Immune Deficiency Syndromes 2021-10-01 2021-07-08 /pmc/articles/PMC8425510/ /pubmed/34238821 http://dx.doi.org/10.1097/QAI.0000000000002758 Text en Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.
spellingShingle Epidemiology
Luan, Hui
Song, Insang
Fiellin, David A.
Ransome, Yusuf
HIV Infection Prevalence Significantly Intersects With COVID-19 Infection At the Area Level: A US County-Level Analysis
title HIV Infection Prevalence Significantly Intersects With COVID-19 Infection At the Area Level: A US County-Level Analysis
title_full HIV Infection Prevalence Significantly Intersects With COVID-19 Infection At the Area Level: A US County-Level Analysis
title_fullStr HIV Infection Prevalence Significantly Intersects With COVID-19 Infection At the Area Level: A US County-Level Analysis
title_full_unstemmed HIV Infection Prevalence Significantly Intersects With COVID-19 Infection At the Area Level: A US County-Level Analysis
title_short HIV Infection Prevalence Significantly Intersects With COVID-19 Infection At the Area Level: A US County-Level Analysis
title_sort hiv infection prevalence significantly intersects with covid-19 infection at the area level: a us county-level analysis
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425510/
https://www.ncbi.nlm.nih.gov/pubmed/34238821
http://dx.doi.org/10.1097/QAI.0000000000002758
work_keys_str_mv AT luanhui hivinfectionprevalencesignificantlyintersectswithcovid19infectionatthearealevelauscountylevelanalysis
AT songinsang hivinfectionprevalencesignificantlyintersectswithcovid19infectionatthearealevelauscountylevelanalysis
AT fiellindavida hivinfectionprevalencesignificantlyintersectswithcovid19infectionatthearealevelauscountylevelanalysis
AT ransomeyusuf hivinfectionprevalencesignificantlyintersectswithcovid19infectionatthearealevelauscountylevelanalysis