Absence of CD11a Expression Identifies Embryonic Hematopoietic Stem Cell Precursors via Competitive Neonatal Transplantation Assay

Hematopoietic stem cells (HSCs) are defined by their self-renewal, multipotency, and bone marrow (BM) engraftment abilities. How HSCs emerge during embryonic development remains unclear, but are thought to arise from hemogenic endothelium through an intermediate precursor called “pre-HSCs.” Pre-HSCs...

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Detalles Bibliográficos
Autores principales: Karimzadeh, Alborz, Varady, Erika S., Scarfone, Vanessa M., Chao, Connie, Grathwohl, Karin, Nguyen, Pauline U., Ghorbanian, Yasamine, Weissman, Irving L., Serwold, Thomas, Inlay, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425522/
https://www.ncbi.nlm.nih.gov/pubmed/34513848
http://dx.doi.org/10.3389/fcell.2021.734176

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