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Amelioration of Hippocampal Insulin Resistance Reduces Tau Hyperphosphorylation and Cognitive Decline Induced by Isoflurane in Mice

General anesthetics can induce cognitive impairments and increase the risk of Alzheimer’s disease (AD). However, the underlying mechanisms are still unknown. Our previous studies shown that long-term isoflurane exposure induced peripheral and central insulin resistance (IR) in adult mice and aggrava...

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Detalles Bibliográficos
Autores principales: Peng, Liangyu, Fang, Xin, Xu, Fangxia, Liu, Shuai, Qian, Yue, Gong, Xiangdan, Zhao, Xin, Ma, Zhengliang, Xia, Tianjiao, Gu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425557/
https://www.ncbi.nlm.nih.gov/pubmed/34512303
http://dx.doi.org/10.3389/fnagi.2021.686506