In vivo trafficking of a tumor-targeting IgE antibody: molecular imaging demonstrates rapid hepatobiliary clearance compared to IgG counterpart

IgE antibodies elicit powerful immune responses, recruiting effector cells to tumors more efficiently and with greater cytotoxicity than IgG antibodies. Consequently, IgE antibodies are a promising alternative to conventional IgG-based therapies in oncology (AllergoOncology). As the pharmacokinetics...

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Detalles Bibliográficos
Autores principales: Man, Francis, Koers, Alexander, Karagiannis, Panagiotis, Josephs, Debra H., Bax, Heather J., Gilbert, Amy E., Dodev, Tihomir S., Mele, Silvia, Chiarruttini, Giulia, Crescioli, Silvia, Chauhan, Jitesh, Blower, Julia E., Cooper, Margaret S., Spicer, James, Karagiannis, Sophia N., Blower, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425638/
https://www.ncbi.nlm.nih.gov/pubmed/34513315
http://dx.doi.org/10.1080/2162402X.2021.1966970

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