Improved anti-cancer effect of epidermal growth factor-gold nanoparticle conjugates by protein orientation through site-specific mutagenesis

Epidermal growth factor (EGF)-nanoparticle conjugates have the potential for cancer therapeutics due to the unique cytotoxic activity in cancer cells with EGF receptor (EGFR) overexpression. To gain its maximum activity, the EGF molecule should be immobilized on the nanoparticle surface in a defined...

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Detalles Bibliográficos
Autores principales: Zhang, Aiwen, Nakanishi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Focus on Trends in Biomaterials in Japan
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425683/
https://www.ncbi.nlm.nih.gov/pubmed/34512175
http://dx.doi.org/10.1080/14686996.2021.1944783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425683/
https://www.ncbi.nlm.nih.gov/pubmed/34512175
http://dx.doi.org/10.1080/14686996.2021.1944783

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