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Gut microbiota associations with metabolic syndrome and relevance of its study in pediatric subjects
Childhood obesity and T2DM have shown a recent alarming increase due to important changes in global lifestyle and dietary habits, highlighting the need for urgent and novel solutions to improve global public health. Gut microbiota has been shown to be relevant in human health and its dysbiosis has b...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425709/ https://www.ncbi.nlm.nih.gov/pubmed/34491882 http://dx.doi.org/10.1080/19490976.2021.1960135 |
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author | Carrizales-Sánchez, Ana K. García-Cayuela, Tomás Hernández-Brenes, Carmen Senés-Guerrero, Carolina |
author_facet | Carrizales-Sánchez, Ana K. García-Cayuela, Tomás Hernández-Brenes, Carmen Senés-Guerrero, Carolina |
author_sort | Carrizales-Sánchez, Ana K. |
collection | PubMed |
description | Childhood obesity and T2DM have shown a recent alarming increase due to important changes in global lifestyle and dietary habits, highlighting the need for urgent and novel solutions to improve global public health. Gut microbiota has been shown to be relevant in human health and its dysbiosis has been associated with MetS, a health condition linked to the onset of relevant diseases including T2DM. Even though there have been recent improvements in the understanding of gut microbiota–host interactions, pediatric gut microbiota has been poorly studied compared to adults. This review provides an overview of MetS and its relevance in school-age children, discusses gut microbiota and its possible association with this metabolic condition including relevant emerging gut microbiome-based interventions for its prevention and treatment, and outlines future challenges and perspectives in preventing microbiota dysbiosis from the early stages of life. |
format | Online Article Text |
id | pubmed-8425709 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-84257092021-09-09 Gut microbiota associations with metabolic syndrome and relevance of its study in pediatric subjects Carrizales-Sánchez, Ana K. García-Cayuela, Tomás Hernández-Brenes, Carmen Senés-Guerrero, Carolina Gut Microbes Review Childhood obesity and T2DM have shown a recent alarming increase due to important changes in global lifestyle and dietary habits, highlighting the need for urgent and novel solutions to improve global public health. Gut microbiota has been shown to be relevant in human health and its dysbiosis has been associated with MetS, a health condition linked to the onset of relevant diseases including T2DM. Even though there have been recent improvements in the understanding of gut microbiota–host interactions, pediatric gut microbiota has been poorly studied compared to adults. This review provides an overview of MetS and its relevance in school-age children, discusses gut microbiota and its possible association with this metabolic condition including relevant emerging gut microbiome-based interventions for its prevention and treatment, and outlines future challenges and perspectives in preventing microbiota dysbiosis from the early stages of life. Taylor & Francis 2021-09-07 /pmc/articles/PMC8425709/ /pubmed/34491882 http://dx.doi.org/10.1080/19490976.2021.1960135 Text en © 2021 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Carrizales-Sánchez, Ana K. García-Cayuela, Tomás Hernández-Brenes, Carmen Senés-Guerrero, Carolina Gut microbiota associations with metabolic syndrome and relevance of its study in pediatric subjects |
title | Gut microbiota associations with metabolic syndrome and relevance of its study in pediatric subjects |
title_full | Gut microbiota associations with metabolic syndrome and relevance of its study in pediatric subjects |
title_fullStr | Gut microbiota associations with metabolic syndrome and relevance of its study in pediatric subjects |
title_full_unstemmed | Gut microbiota associations with metabolic syndrome and relevance of its study in pediatric subjects |
title_short | Gut microbiota associations with metabolic syndrome and relevance of its study in pediatric subjects |
title_sort | gut microbiota associations with metabolic syndrome and relevance of its study in pediatric subjects |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425709/ https://www.ncbi.nlm.nih.gov/pubmed/34491882 http://dx.doi.org/10.1080/19490976.2021.1960135 |
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