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Prospective Evaluation of Clinical Outcomes Using a Multiplex Liquid Biopsy Targeting Diverse Resistance Mechanisms in Metastatic Prostate Cancer

Nearly all men with prostate cancer treated with androgen receptor (AR) signaling inhibitors (ARSIs) develop resistance via diverse mechanisms including constitutive activation of the AR pathway, driven by AR genomic structural alterations, expression of AR splice variants (AR-Vs), or loss of AR dep...

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Detalles Bibliográficos
Autores principales: Sperger, Jamie M., Emamekhoo, Hamid, McKay, Rana R., Stahlfeld, Charlotte N., Singh, Anupama, Chen, Xinyi E., Kwak, Lucia, Gilsdorf, Cole S., Wolfe, Serena K., Wei, Xiao X., Silver, Rebecca, Zhang, Zhenwei, Morris, Michael J., Bubley, Glenn, Feng, Felix Y., Scher, Howard I., Rathkopf, Dana, Dehm, Scott M., Choueiri, Toni K., Halabi, Susan, Armstrong, Andrew J., Wyatt, Alexander W., Taplin, Mary-Ellen, Zhao, Shuang G., Lang, Joshua M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425833/
https://www.ncbi.nlm.nih.gov/pubmed/34197212
http://dx.doi.org/10.1200/JCO.21.00169

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